The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells.

Animals Cell Proliferation / physiology Cell Self Renewal Hematopoiesis / physiology Hematopoietic Stem Cells / metabolism Mice Mice, Inbred C57BL Mice, Knockout Repressor Proteins / metabolism

Journal

Blood
ISSN: 1528-0020
Titre abrégé: Blood
Pays: United States
ID NLM: 7603509

Informations de publication

Date de publication:
06 06 2019
Historique:
received: 31 07 2018
accepted: 26 03 2019
pubmed: 29 3 2019
medline: 10 1 2020
entrez: 29 3 2019
Statut: ppublish

Résumé

Recurrent inactivating mutations have been identified in the X-linked plant homeodomain finger protein 6 (

Identifiants

DOI: 10.1182/blood.2019000468 PMID: 30917958
pubmed: 30917958
pii: S0006-4971(20)42503-0
doi: 10.1182/blood.2019000468
doi:

Substances chimiques

Phf6 protein, mouse 0
Repressor Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2495-2506

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2019 by The American Society of Hematology.

Auteurs

Satoru Miyagi (S)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
Department of Life Science, Faculty of Medicine, Shimane University, Izumo, Japan.

Patrycja Sroczynska (P)

Biotech Research and Innovation Centre (BRIC) and.
The Novo Nordisk Center for Stem Cell Biology (DanStem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Yuko Kato (Y)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
Department of Life Science, Faculty of Medicine, Shimane University, Izumo, Japan.

Yaeko Nakajima-Takagi (Y)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Motohiko Oshima (M)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Ola Rizq (O)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Naoya Takayama (N)

Department of Regenerative Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Atsunori Saraya (A)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Seiya Mizuno (S)

Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan; and.

Fumihiro Sugiyama (F)

Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan; and.

Satoru Takahashi (S)

Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan; and.

Yumi Matsuzaki (Y)

Department of Life Science, Faculty of Medicine, Shimane University, Izumo, Japan.

Jesper Christensen (J)

Biotech Research and Innovation Centre (BRIC) and.
The Novo Nordisk Center for Stem Cell Biology (DanStem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Kristian Helin (K)

Biotech Research and Innovation Centre (BRIC) and.
The Novo Nordisk Center for Stem Cell Biology (DanStem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Atsushi Iwama (A)

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
ORCID: 0000-0001-9410-8992

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Division cellulaire › Auto-renouvellement cellulaire › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hématopoïèse › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système hématopoïétique › Cellules de la moelle osseuse › Cellules souches hématopoïétiques › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › The chromatin-binding protein Phf6 restricts...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéines de répression › The chromatin-binding protein Phf6 restricts...