Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma.
Antineoplastic Agents
/ therapeutic use
Crohn Disease
/ complications
Gastrointestinal Agents
/ therapeutic use
Humans
Intestine, Small
/ physiopathology
Japan
Male
Middle Aged
Neoplasm Recurrence, Local
/ complications
Plasmacytoma
/ diagnosis
Treatment Outcome
Tumor Necrosis Factor-alpha
/ antagonists & inhibitors
Crohn's disease (CD)
anti-TNFα agents
extramedullary plasmacytoma (EMP)
plasmablastic lymphoma (PBL)
plasmablastic neoplasm
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 Jul 2019
15 Jul 2019
Historique:
pubmed:
29
3
2019
medline:
13
11
2019
entrez:
29
3
2019
Statut:
ppublish
Résumé
We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A stenosed site of ileo-cecal anastomosis was identified and therefore was surgically resected, which was diagnosed as CD with small intestinal extramedullary plasmacytoma (EMP). The subsequent progression of CD was successfully controlled by anti-TNFα agents without any recurrence of EMP for over 3 years, implying the clinical benefit and safety of the biological therapy. This was the first known case of a patient who received anti-TNFα agents after a resection of small intestinal EMP accompanied with CD.
Identifiants
pubmed: 30918171
doi: 10.2169/internalmedicine.1687-18
pmc: PMC6702015
doi:
Substances chimiques
Antineoplastic Agents
0
Gastrointestinal Agents
0
Tumor Necrosis Factor-alpha
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2019-2023Références
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