Genome-wide association study of psoriasis in an Egyptian population.
Egyptian
genome-wide association study
psoriasis
Journal
Experimental dermatology
ISSN: 1600-0625
Titre abrégé: Exp Dermatol
Pays: Denmark
ID NLM: 9301549
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
24
09
2018
revised:
12
02
2019
accepted:
01
03
2019
pubmed:
29
3
2019
medline:
30
9
2020
entrez:
29
3
2019
Statut:
ppublish
Résumé
Psoriasis is a chronic inflammatory disorder of the skin, with genetic factors reportedly involved in the disease pathogenesis. Numerous studies reported psoriasis candidate genes. However, these tend to involve mostly in the European and Asian populations. Here, we report the first genome-wide association study (GWAS) in an Egyptian population, identifying susceptibility variants for psoriasis using a two-stage case-control design. In the first discovery stage, we carried out a genome-wide association analysis using the Infinium
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
623-627Subventions
Organisme : German Science Foundation
Pays : International
Organisme : DFG
ID : EXC 306
Pays : International
Organisme : DFG
ID : GRK1743
Pays : International
Organisme : University of Lübeck
Pays : International
Informations de copyright
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.