Immunohistochemistry for Anti-diabetes Drug, Alogliptin Using a Newly Prepared Monoclonal Antibody: Its Precise Localization in Rat Small Intestine.

alogliptin immunohistochemistry intestine localization rat

Journal

Acta histochemica et cytochemica
ISSN: 0044-5991
Titre abrégé: Acta Histochem Cytochem
Pays: Japan
ID NLM: 0147110

Informations de publication

Date de publication:
28 Feb 2019
Historique:
received: 16 10 2018
accepted: 10 01 2019
entrez: 30 3 2019
pubmed: 30 3 2019
medline: 30 3 2019
Statut: ppublish

Résumé

Knowledge of time sequence of localization of drugs in cells and tissues of animals may help in developing a better understanding of the actual overall pharmacokinetics of the drugs. We produced monoclonal antibody (mAb) against alogliptin (AG), a dipeptidyl peptidase-4 (DPP-4) inhibitor, conjugated to BSA with

Identifiants

pubmed: 30923413
doi: 10.1267/ahc.18036
pii: JST.JSTAGE/ahc/18036
pmc: PMC6434317
doi:

Types de publication

Journal Article

Langues

eng

Pagination

27-34

Déclaration de conflit d'intérêts

VThe authors declare no conflicts of interest.

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Auteurs

Yuta Yamamoto (Y)

Department of Applied Life Science, Faculty of Biotechnology and Life Science, Sojo University, 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082, Japan.

Yutaro Yamamoto (Y)

Department of Applied Life Science, Faculty of Biotechnology and Life Science, Sojo University, 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082, Japan.

Tetsuya Saita (T)

Department of Applied Life Science, Faculty of Biotechnology and Life Science, Sojo University, 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082, Japan.

Masashi Shin (M)

Department of Applied Life Science, Faculty of Biotechnology and Life Science, Sojo University, 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082, Japan.

Classifications MeSH