Quality of Life of Caregivers of Older Patients with Advanced Cancer.
Adult
Aged
Aged, 80 and over
Anxiety
/ epidemiology
Caregivers
/ psychology
Cognition
Cross-Sectional Studies
Depression
/ epidemiology
Emotions
Female
Geriatric Assessment
/ methods
Humans
Incidence
Male
Mental Health
Middle Aged
Neoplasms
/ therapy
Quality of Life
/ psychology
Surveys and Questionnaires
United States
/ epidemiology
caregivers
emotional health
geriatric assessment
quality of life
Journal
Journal of the American Geriatrics Society
ISSN: 1532-5415
Titre abrégé: J Am Geriatr Soc
Pays: United States
ID NLM: 7503062
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
01
10
2018
revised:
03
12
2018
accepted:
09
12
2018
pubmed:
30
3
2019
medline:
15
5
2020
entrez:
30
3
2019
Statut:
ppublish
Résumé
To evaluate the relationships between aging-related domains captured by geriatric assessment (GA) for older patients with advanced cancer and caregivers' emotional health and quality of life (QOL). In this cross sectional study of baseline data from a nationwide investigation of older patients and their caregivers, patients completed a GA that included validated tests to evaluate eight domains of health (eg, function, cognition). Thirty-one community oncology practices throughout the United States. Enrolled patients were aged 70 and older, had one or more GA domain impaired, and had an incurable solid tumor malignancy or lymphoma. Each could choose one caregiver to enroll. Caregivers completed the Generalized Anxiety Disorder-7, Distress Thermometer, Patient Health Questionnaire-2 (depression), and Short Form Health Survey-12 (SF-12 for QOL). Separate multivariate linear or logistic regression models were used to examine the association of the number and type of patient GA impairments with caregiver outcomes, controlling for patient and caregiver covariates. A total of 541 patients were enrolled, 414 with a caregiver. Almost half (43.5%) of the caregivers screened positive for distress, 24.4% for anxiety, and 18.9% for depression. Higher numbers of patient GA domain impairments were associated with caregiver depression (adjusted odds ratio [aOR] = 1.29; P < .001], caregiver physical health on SF-12 (regression coefficient [β] = -1.24; P < .001), and overall caregiver QOL (β = -1.14; P < .01). Impaired patient function was associated with lower caregiver QOL (β = -4.11; P < .001). Impaired patient nutrition was associated with caregiver depression (aOR = 2.08; P < .01). Lower caregiver age, caregiver comorbidity, and patient distress were also associated with worse caregiver outcomes. Patient GA impairments were associated with poorer emotional health and lower QOL of caregivers. J Am Geriatr Soc 67:969-977, 2019.
Identifiants
pubmed: 30924548
doi: 10.1111/jgs.15862
pmc: PMC7818364
mid: NIHMS1660339
doi:
Banques de données
ClinicalTrials.gov
['NCT02107443']
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
969-977Subventions
Organisme : NIA NIH HHS
ID : R21 AG059206
Pays : United States
Organisme : Patient-Centered Outcomes Research Institute
ID : 4634
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA189961
Pays : United States
Organisme : NIA NIH HHS
ID : R33 AG059206
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA177592
Pays : United States
Organisme : NIA NIH HHS
ID : K24 AG056589
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2019 The American Geriatrics Society.
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