Interpolated CT for attenuation correction on respiratory gating cardiac SPECT/CT - A simulation study.


Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Jun 2019
Historique:
received: 19 09 2018
revised: 07 03 2019
accepted: 18 03 2019
pubmed: 30 3 2019
medline: 23 11 2019
entrez: 30 3 2019
Statut: ppublish

Résumé

Respiratory gated four-dimensional (4D) single photon emission computed tomography (SPECT) with phase-matched CT reduces respiratory blurring and attenuation correction (AC) artifacts in cardiac SPECT. This study aims to develop and investigate the effectiveness of an interpolated CT (ICT) method for improved cardiac SPECT AC using simulations. We used the 4D XCAT phantom to simulate a population of ten patients varied in gender, anatomy, The average of maximum relative difference through ten phantoms was 7.93 ± 4.71%, 2.50 ± 0.98%, 3.58 ± 0.74%, and 2.14 ± 0.56% for noisy HCT-IN, HCT-MID, HCT-EX, and ICT AC data, respectively. The ICT showed closest defect size to GCT while the differences from HCTs can be over 40%. We conclude that the performance of ICT is similar to GCT. It improves the image quality and quantitative accuracy for respiratory-gated cardiac SPECT as compared to conventional HCT, while it can potentially further reduce the radiation dose of GCT.

Identifiants

pubmed: 30924935
doi: 10.1002/mp.13513
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2621-2628

Subventions

Organisme : National Natural Science Foundation of China
ID : 81601525
Organisme : Macau Science and Technology Development Fund
ID : 114/2016/A3
Organisme : University of Macau
ID : MYRG2016-00091-FST

Informations de copyright

© 2019 American Association of Physicists in Medicine.

Auteurs

Duo Zhang (D)

Biomedical Imaging Laboratory (BIG), Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.

Michael Ghaly (M)

Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
Radiopharmaceutical Imaging and Dosimetry (RAPID), LLC, Baltimore, MD, USA.

Greta S P Mok (GSP)

Biomedical Imaging Laboratory (BIG), Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.
Faculty of Health Sciences, University of Macau, Macau SAR, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH