The Quest for an Ideal Neoadjuvant Systemic Therapy in Cisplatin-Ineligible Patients with Muscle-Invasive Localized Urothelial Carcinoma.


Journal

The oncologist
ISSN: 1549-490X
Titre abrégé: Oncologist
Pays: England
ID NLM: 9607837

Informations de publication

Date de publication:
05 2019
Historique:
received: 24 02 2019
accepted: 28 02 2019
pubmed: 31 3 2019
medline: 7 2 2020
entrez: 31 3 2019
Statut: ppublish

Résumé

This commentary reviews current progress in neoadjuvant immunotherapy for muscle‐invasive localized urothelial carcinoma, highlighting opportunities and challenges with recent neoadjuvant immunotherapy trials.

Identifiants

pubmed: 30926675
pii: theoncologist.2019-0161
doi: 10.1634/theoncologist.2019-0161
pmc: PMC6516125
doi:

Substances chimiques

Cisplatin Q20Q21Q62J

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

580-583

Commentaires et corrections

Type : CommentOn

Déclaration de conflit d'intérêts

Disclosures of potential conflicts of interest may be found at the end of this article.

Références

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J Clin Oncol. 2018 Oct 20;:JCO1801148
pubmed: 30343614
Oncologist. 2019 May;24(5):688-690
pubmed: 30728277
Cancer. 2008 Nov 1;113(9):2471-7
pubmed: 18823036
Nature. 2014 Mar 20;507(7492):315-22
pubmed: 24476821
Cancer. 2006 Aug 1;107(3):506-13
pubmed: 16773629
Ann Transl Med. 2018 Jun;6(12):250
pubmed: 30069452
J Clin Oncol. 2011 Jun 10;29(17):2432-8
pubmed: 21555688
Eur Urol. 2015 Jan;67(1):165-170
pubmed: 24472710
J Clin Oncol. 2011 Jun 1;29(16):2171-7
pubmed: 21502557
Clin Genitourin Cancer. 2018 Aug;16(4):e879-e892
pubmed: 29576445
N Engl J Med. 2003 Aug 28;349(9):859-66
pubmed: 12944571
Eur Urol. 2005 Aug;48(2):202-5; discussion 205-6
pubmed: 15939524

Auteurs

Umang Swami (U)

Department of Hematology, Oncology and Blood and Marrow Transplantation, The Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Petros Grivas (P)

Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Clinical Research Division, Fred Hutchison Cancer Research Center, Seattle Cancer Care Alliance, Seattle, Washington, USA.

Neeraj Agarwal (N)

Division of Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA neeraj.agarwal@hci.utah.edu.

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Classifications MeSH