Two novel azaspiracids from Azadinium poporum, and a comprehensive compilation of azaspiracids produced by Amphidomataceae, (Dinophyceae).
Amphidoma
Azadinium
Azaspiracid shellfish poisoning (AZP)
CID spectrum
LC–MS/MS
Toxic dinoflagellates
Journal
Harmful algae
ISSN: 1878-1470
Titre abrégé: Harmful Algae
Pays: Netherlands
ID NLM: 101128968
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
16
10
2018
revised:
26
11
2018
accepted:
18
12
2018
entrez:
1
4
2019
pubmed:
1
4
2019
medline:
23
2
2020
Statut:
ppublish
Résumé
Two novel azaspiracids (AZA) with a molecular mass of 869 Da were found in Pacific strains of Azadinium poporum and characterized by tandem mass spectrometry and high resolution mass spectrometry (HRMS). One compound, AZA-42, was found in Az. poporum strains AZFC25 and AZFC26, both isolated from the South China Sea. AZA-42 belongs to the 360-type AZA that in comparison to AZA-1 has an additional double bond in the F-I ring system of AZA comprising C28-C40. The other compound, AZA-62, was detected in Az. poporum strain 1D5 isolated off Chañaral, Northern Chile. Mass spectral data indicate that AZA-62 is a variant of AZA-11 with an additional double bond in the C1-C9 region of AZA. In addition to the description of the two novel AZA, a comprehensive list of all AZA known to be produced by species of the genera Azadinium and Amphidoma comprising 26 AZA variants is presented.
Identifiants
pubmed: 30928006
pii: S1568-9883(18)30193-8
doi: 10.1016/j.hal.2018.12.005
pii:
doi:
Substances chimiques
Marine Toxins
0
Spiro Compounds
0
azaspiracid
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-8Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.