Determination of midazolam dose for co-induction with alfaxalone in sedated cats.
Anesthesia
/ veterinary
Anesthetics, Combined
/ administration & dosage
Animals
Cats
Cross-Over Studies
Dexmedetomidine
/ administration & dosage
Dose-Response Relationship, Drug
Female
Intubation, Intratracheal
/ veterinary
Male
Midazolam
/ administration & dosage
Pregnanediones
/ administration & dosage
Random Allocation
alfaxalone
anesthesia
cats
co-induction
midazolam
up-and-down
Journal
Veterinary anaesthesia and analgesia
ISSN: 1467-2995
Titre abrégé: Vet Anaesth Analg
Pays: United States
ID NLM: 100956422
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
20
04
2018
revised:
23
12
2018
accepted:
09
01
2019
pubmed:
1
4
2019
medline:
7
6
2019
entrez:
1
4
2019
Statut:
ppublish
Résumé
To investigate the median effective dose 50 (ED Randomized up-and-down study. A group of 14 mixed-breed cats (eight males, six females), aged 5-12 years and weighing 4.4-6.8 kg. The cats were randomly assigned in a sequential allocation numbers from one to 14. Cats were sedated with dexmedetomidine (3 μg kg Overall, six independent crossovers were found, and ED This study determined that 0.08 ± 0.04 mg kg
Identifiants
pubmed: 30928240
pii: S1467-2987(19)30014-5
doi: 10.1016/j.vaa.2019.01.006
pii:
doi:
Substances chimiques
Anesthetics, Combined
0
Pregnanediones
0
Dexmedetomidine
67VB76HONO
alphaxalone
BD07M97B2A
Midazolam
R60L0SM5BC
Types de publication
Clinical Trial, Veterinary
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
299-307Informations de copyright
Copyright © 2019 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.