Screening of antibacterial drugs for antimicrobial activity against Pythium insidiosum.
in vitro susceptibility
antibacterial agents
oomycete
pythiosis
therapy
Journal
Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835
Informations de publication
Date de publication:
01 Jun 2019
01 Jun 2019
Historique:
received:
31
03
2018
revised:
24
05
2018
accepted:
07
07
2018
entrez:
1
4
2019
pubmed:
1
4
2019
medline:
30
4
2019
Statut:
ppublish
Résumé
We tested 25 isolates of Pythium insidiosum to investigate their susceptibility to antibacterial drugs that act through inhibition of protein synthesis or other mechanisms of action. We observed that tetracycline, erythromycin, linezolid, nitrofurantoin, Synercid (quinupristin and dalfopristin), chloramphenicol, clindamycin, cetrimide, and crystal violet had inhibitory activity against P. insidiosum. Those in vitro results suggest that antibacterials that inhibit protein synthesis should be the primary antimicrobials investigated for the treatment of pythiosis in animals and humans.
Identifiants
pubmed: 30929019
pii: 5060214
doi: 10.1093/mmy/myy056
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antifungal Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
523-525Informations de copyright
© The Author(s) 2018. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.