Studies on B Cells in the Fruit-Eating Black Flying Fox (


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2019
Historique:
received: 10 07 2018
accepted: 22 02 2019
entrez: 2 4 2019
pubmed: 2 4 2019
medline: 4 9 2020
Statut: epublish

Résumé

The ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of their immune system. However, the lack of bat specific reagents, in particular antibodies, has limited our knowledge of bat's immunity. Here, we report a panel of cross-reactive antibodies against MHC-II, NK1.1, CD3, CD21, CD27, and immunoglobulin (Ig), that allows flow cytometry analysis of B, T and NK cell populations in two different fruit-eating bat species namely,

Identifiants

pubmed: 30930908
doi: 10.3389/fimmu.2019.00489
pmc: PMC6428034
doi:

Substances chimiques

Antigens, Differentiation 0
Receptors, Antigen, B-Cell 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

489

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Auteurs

Pravin Periasamy (P)

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Paul E Hutchinson (PE)

Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Jinmiao Chen (J)

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.

Isabelle Bonne (I)

Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Shahana Shereene Shahul Hameed (SS)

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Pavithra Selvam (P)

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Ying Ying Hey (YY)

Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore, Singapore.

Katja Fink (K)

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.

Aaron T Irving (AT)

Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore, Singapore.

Charles-Antoine Dutertre (CA)

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.

Michelle Baker (M)

CSIRO, Livestock Industries, Australian Animal Health Laboratory, Geelong, VIC, Australia.

Gary Crameri (G)

Crameri Research Consulting, Geelong, VIC, Australia.

Lin-Fa Wang (LF)

Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore, Singapore.

Sylvie Alonso (S)

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

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Classifications MeSH