Identification of the first enantiopure Rac1-Tiam1 protein-protein interaction inhibitor and its optimized synthesis
Journal
MedChemComm
ISSN: 2040-2511
Titre abrégé: Medchemcomm
Pays: England
ID NLM: 101531525
Informations de publication
Date de publication:
01 Feb 2019
01 Feb 2019
Historique:
received:
24
09
2018
accepted:
21
12
2018
entrez:
2
4
2019
pubmed:
2
4
2019
medline:
2
4
2019
Statut:
epublish
Résumé
A phospine free hydroarylation reaction applied to norbornene derivatives is described for the first time and was exploited for the regioselective gram scale synthesis of
Identifiants
pubmed: 30931091
doi: 10.1039/c8md00477c
pii: c8md00477c
pmc: PMC6396393
doi:
Types de publication
Journal Article
Langues
eng
Pagination
310-314Références
J Clin Invest. 2000 Apr;105(7):875-86
pubmed: 10749567
J Org Chem. 2001 Jul 27;66(15):5182-91
pubmed: 11463272
Org Lett. 2003 Sep 4;5(18):3285-8
pubmed: 12943408
Proc Natl Acad Sci U S A. 2004 May 18;101(20):7618-23
pubmed: 15128949
J Chem Inf Model. 2006 Mar-Apr;46(2):525-35
pubmed: 16562980
Proc Natl Acad Sci U S A. 2006 May 9;103(19):7432-7
pubmed: 16651530
J Am Chem Soc. 2006 Oct 4;128(39):12785-93
pubmed: 17002373
Cardiovasc Res. 2008 Nov 1;80(2):290-8
pubmed: 18599477
J Med Chem. 2009 Jul 23;52(14):4087-90
pubmed: 19527032
J Med Chem. 2009 Nov 12;52(21):6752-6
pubmed: 19827778
J Am Chem Soc. 2010 Jan 13;132(1):79-81
pubmed: 20014842
P R Health Sci J. 2010 Dec;29(4):348-56
pubmed: 21261173
J Biol Chem. 2012 Apr 13;287(16):13228-38
pubmed: 22383527
Cardiovasc Res. 2012 Aug 1;95(3):366-74
pubmed: 22721990
J Med Chem. 2014 Apr 10;57(7):2953-62
pubmed: 24520998
Onco Targets Ther. 2014 Oct 30;7:2021-33
pubmed: 25378937
J Thromb Haemost. 2015 May;13(5):827-38
pubmed: 25628054
PLoS One. 2015 Nov 11;10(11):e0142182
pubmed: 26558612
Science. 1996 Feb 16;271(5251):981-3
pubmed: 8584934