Tc-99m HYNIC-TOC scintigraphy in dedifferentiated thyroid cancer.
dedifferentiated
endocrine system
thyroid cancer
thyroid disease
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
01 Apr 2019
01 Apr 2019
Historique:
entrez:
4
4
2019
pubmed:
4
4
2019
medline:
26
7
2019
Statut:
epublish
Résumé
There is literature evidence showing utility of somatostatin receptor (SSTR) positron emission tomography-CT (PET-CT) imaging in differentiated thyroid cancer with Thyroglobulin Elevated and Negative Iodine Scan (TENIS). These patients are less benefited with I-131 therapy and surgery remains only curable option if disease could be localised. If surgery is not feasible, other therapeutic options are not promising. However, if these patients show strongly positive SSTR imaging, then possibility of peptide receptor radionuclide therapy may be explored. As SSTR PET-CT imaging is expensive and not widely available, Technetium-99m (Tc-99m) hydrazinonicotinyl-Tyr3-octreotide (HYNIC-TOC), which is a Single photon emission computed tomography (SPECT) tracer, can be used. We are documenting a case of raised serum thyroglobulin antibody and negative I-131 whole body scan with disease recurrence localised on Tc-99m HYNIC-TOC scan.
Identifiants
pubmed: 30940668
pii: 12/4/e227910
doi: 10.1136/bcr-2018-227910
pmc: PMC6453278
pii:
doi:
Substances chimiques
Iodine Radioisotopes
0
Organotechnetium Compounds
0
technetium Tc 99m hydrazinonicotinyl-Tyr(3)-octreotide
0
Octreotide
RWM8CCW8GP
Types de publication
Case Reports
Journal Article
Langues
eng
Informations de copyright
© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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