Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting.


Journal

Pigment cell & melanoma research
ISSN: 1755-148X
Titre abrégé: Pigment Cell Melanoma Res
Pays: England
ID NLM: 101318927

Informations de publication

Date de publication:
09 2019
Historique:
received: 13 12 2018
revised: 10 03 2019
accepted: 27 03 2019
pubmed: 5 4 2019
medline: 26 3 2020
entrez: 5 4 2019
Statut: ppublish

Résumé

Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21-1.67], moderate 3.17 [IQR: 1.75-6.21], extensive 9.58 [IQR: 6.21-13.03] and very extensive 42.67 [IQR: 21.20-42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.

Identifiants

pubmed: 30945409
doi: 10.1111/pcmr.12784
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

728-733

Investigateurs

Tag Anbar (T)
Mohamed Anbar (M)
Laïla Benzekri (L)
Markus Böhm (M)
Caïo Castro (C)
Tania Cestari (T)
Yvon Gauthier (Y)
Maria Gnarra (M)
Jorge Hinojosa (J)
Min Bae Jung (MB)
Ichiro Katayama (I)
Ki-Ho Kim (KH)
Cheng-Che Eric Lan (CC)
Seung-Chung Lee (SC)
Caroline Le Poole (C)
Henry Lim (H)
Silvia Moretti (S)
Julien Seneschal (J)
Richard Spritz (R)
Nanja van Geel (N)
Flora Xiang (F)

Informations de copyright

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Références

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Auteurs

Nanja van Geel (N)

Department of Dermatology, Ghent University Hospital, Ghent, Belgium.

Albert Wolkerstorfer (A)

Department of Dermatology, Institute for Pigment Disorders and Infection, Immunity Institute Amsterdam UMC, Amsterdam, The Netherlands.

Khaled Ezzedine (K)

Department of Dermatology, Henri Mondor Hospital, UPE-Université Paris-Est, Créteil, France.

Amit G Pandya (AG)

Department of Dermatology, The University of Texas Southwestern Medical Center, Dallas, Texas.

Marcel Bekkenk (M)

Department of Dermatology, Institute for Pigment Disorders and Infection, Immunity Institute Amsterdam UMC, Amsterdam, The Netherlands.

Lynda Grine (L)

Department of Dermatology, Ghent University Hospital, Ghent, Belgium.

Sarah Van Belle (S)

Department of Dermatology, Ghent University Hospital, Ghent, Belgium.

Janny E Lommerts (JE)

Department of Dermatology, Institute for Pigment Disorders and Infection, Immunity Institute Amsterdam UMC, Amsterdam, The Netherlands.

Iltefat Hamzavi (I)

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

John E Harris (JE)

Department of Dermatology, The University of Massachusetts Medical School, Worcester, Massachusetts.

Viktoria Eleftheriadou (V)

Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, UK.

Samia Esmat (S)

Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Hee Young Kang (HY)

Department of dermatology, Ajou University School of Medicine, Suwon, Korea.

Prasad Kumarasinghe (P)

Department of Dermatology, Fiona Stanley Hospital, University of Western Australia, Perth, Western Australia, Australia.

Cheng-Che E Lan (CE)

Department of Dermatology, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Davinder Parsad (D)

Department of Dermatology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Noufal Raboobee (N)

Department of Dermatology, Westville Hospital, Westville, South Africa.

Leihong Flora Xiang (L)

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

Tamio Suzuki (T)

Department of Dermatology, Faculty of Medicine, Yamagata University, Yamagata, Japan.

Cecilia A Prinsen (CA)

Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.

Alain Taieb (A)

Department of Dermatology, INSERM U 1035, Bordeaux University Hospitals, University of Bordeaux, Bordeaux, France.

Mauro Picardo (M)

San Gallicano Dermatologic Institute, Rome, Italy.

Reinhart Speeckaert (R)

Department of Dermatology, Ghent University Hospital, Ghent, Belgium.

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