Oxidative Coupling of 3-Oxindoles with Indoles and Arenes.

catalysis coinage metals oxidative coupling oxygen sustainable

Journal

ChemSusChem
ISSN: 1864-564X
Titre abrégé: ChemSusChem
Pays: Germany
ID NLM: 101319536

Informations de publication

Date de publication:
05 Jul 2019
Historique:
received: 14 02 2019
revised: 03 04 2019
pubmed: 5 4 2019
medline: 5 4 2019
entrez: 5 4 2019
Statut: ppublish

Résumé

A highly efficient method for the oxidative coupling of 2-substituted 3-oxindoles with aromatic compounds to form 2,2-disubstituted indolin-3-ones with broad scope is described. This work utilized oxygen as the terminal oxidant and a base-metal catalyst under mild conditions instead of toxic/precious-metal reagents and higher-molecular-weight oxidants. Quaternary structures were produced in modest-to-excellent yields (up to 96 %) without prefunctionalization.

Identifiants

pubmed: 30945447
doi: 10.1002/cssc.201900438
pmc: PMC6703824
mid: NIHMS1032889
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3144-3151

Subventions

Organisme : Directorate for Biological Sciences
ID : CHE1764298)
Organisme : NCRR NIH HHS
ID : S10 RR023444
Pays : United States
Organisme : NIH HHS
ID : GM-112684
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR022442
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM112684
Pays : United States
Organisme : NIH HHS
ID : S10 OD011980
Pays : United States

Informations de copyright

© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Auteurs

Houng Kang (H)

Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.

Adriana L Jemison (AL)

Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.

Erin Nigro (E)

Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.

Marisa C Kozlowski (MC)

Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.

Classifications MeSH