Increasing waist circumference is associated with decreased levels of glycated albumin.

Adult Aged Aged, 80 and over Blood Glucose / metabolism False Negative Reactions Female Glycated Hemoglobin / metabolism Glycation End Products, Advanced Humans Male Middle Aged Obesity / blood Serum Albumin / metabolism Waist Circumference Glycated Serum Albumin
Central obesity Glycated albumin Glycated hemoglobin A(1c) Hyperglycemia Waist circumference

Journal

Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
Titre abrégé: Clin Chim Acta
Pays: Netherlands
ID NLM: 1302422

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 06 02 2019
revised: 13 03 2019
accepted: 01 04 2019
pubmed: 5 4 2019
medline: 4 12 2019
entrez: 5 4 2019
Statut: ppublish

Résumé

Glycated albumin (GA) levels are affected by body fat and its distribution. We explored the association of waist circumference (WC) with GA and to assess the extent to which WC influences GA. We recruited 1799 subjects (age 26-82 y) from communities. GA was determined using the enzyme method, and glycated hemoglobin A Subjects with central obesity had lower GA and GA/HbA The GA value was reduced by approximately 0.15% for each 5 cm increment in WC, suggesting that more attention should be paid to actual blood glucose underestimated by GA in obese people.

Sections du résumé

BACKGROUND BACKGROUND
Glycated albumin (GA) levels are affected by body fat and its distribution. We explored the association of waist circumference (WC) with GA and to assess the extent to which WC influences GA.
METHODS METHODS
We recruited 1799 subjects (age 26-82 y) from communities. GA was determined using the enzyme method, and glycated hemoglobin A
RESULTS RESULTS
Subjects with central obesity had lower GA and GA/HbA
CONCLUSIONS CONCLUSIONS
The GA value was reduced by approximately 0.15% for each 5 cm increment in WC, suggesting that more attention should be paid to actual blood glucose underestimated by GA in obese people.

Identifiants

DOI: 10.1016/j.cca.2019.04.001 PMID: 30946814
pubmed: 30946814
pii: S0009-8981(19)31742-5
doi: 10.1016/j.cca.2019.04.001
pii:
doi:

Substances chimiques

Blood Glucose 0
Glycated Hemoglobin A 0
Glycation End Products, Advanced 0
Serum Albumin 0
hemoglobin A1c protein, human 0
Glycated Serum Albumin 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

118-122

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Yiting Xu (Y)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China.

Xiaojing Ma (X)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China. Electronic address: maxiaojing@sjtu.edu.cn.

Yun Shen (Y)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China.

Yufei Wang (Y)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China.

Jian Zhou (J)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China.

Yuqian Bao (Y)

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China. Electronic address: yqbao@sjtu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Increasing waist circumference is associated...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Increasing waist circumference is associated...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › Increasing waist circumference is associated...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Glycémie › Increasing waist circumference is associated...
questionsmedicales.fr › Diagnostic › Faux négatifs › Increasing waist circumference is associated...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Produits terminaux de glycation avancée › Protéines glyquées › Protéine glycosylée sérique › Hémoglobine glycosylée › Increasing waist circumference is associated...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Produits terminaux de glycation avancée › Increasing waist circumference is associated...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Increasing waist circumference is associated...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Increasing waist circumference is associated...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Increasing waist circumference is associated...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Increasing waist circumference is associated...
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Poids et mesures du corps › Tour de taille › Increasing waist circumference is associated...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Produits terminaux de glycation avancée › Protéines glyquées › Protéine glycosylée sérique › Albumine sérique glycosylée › Increasing waist circumference is associated...