Metastatic bone disease from an occult renal primary.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
03 Apr 2019
Historique:
entrez: 6 4 2019
pubmed: 6 4 2019
medline: 6 8 2019
Statut: epublish

Résumé

We report a rare presentation of metastatic renal cell carcinoma (RCC) in a 71-year-old man who presented with persistent shoulder pain. MRI revealed widespread lytic lesions within the bones suggestive of metastatic disease but extensive imaging including CT chest, abdomen and pelvis with contrast and fluorodeoxyglucose-positron emission tomography did not identify a primary cancer. The diagnosis was ultimately made from a targeted bone and subsequently targeted liver biopsy, whereby immunohistochemistry was consistent with metastatic RCC (mRCC). While bone metastases in RCC are very common, it is extremely rare for patients to present with mRCC and no identifiable renal primary.

Identifiants

pubmed: 30948394
pii: 12/4/e227657
doi: 10.1136/bcr-2018-227657
pmc: PMC6453267
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Informations de copyright

© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Curr Oncol. 2014 Jun;21(3):e521-4
pubmed: 24940113
BMJ Open. 2017 Sep 11;7(9):e016022
pubmed: 28893744

Auteurs

Laura Woodhouse (L)

Oncology, Royal Free London NHS Foundation Trust, London, UK.

Jennifer Watkins (J)

Pathology, Royal Free London NHS Foundation Trust, London, UK.

Shaunak Navalkissoor (S)

Nuclear Medicine, Royal Free London NHS Foundation Trust, London, UK.

Roopinder Gillmore (R)

Oncology, Royal Free London NHS Foundation Trust, London, UK.

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Classifications MeSH