Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities.
bacteriotherapy
cancer
chemotherapy
immunotherapy
radiotherapy
tumoricidal agents
Journal
Cancer medicine
ISSN: 2045-7634
Titre abrégé: Cancer Med
Pays: United States
ID NLM: 101595310
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
08
03
2019
revised:
17
03
2019
accepted:
20
03
2019
pubmed:
6
4
2019
medline:
8
7
2020
entrez:
6
4
2019
Statut:
ppublish
Résumé
Successful treatment of cancer remains a challenge, due to the unique pathophysiology of solid tumors, and the predictable emergence of resistance. Traditional methods for cancer therapy including radiotherapy, chemotherapy, and immunotherapy all have their own limitations. A novel approach is bacteriotherapy, either used alone, or in combination with conventional methods, has shown a positive effect on regression of tumors and inhibition of metastasis. Bacteria-assisted tumor-targeted therapy used as therapeutic/gene/drug delivery vehicles has great promise in the treatment of tumors. The use of bacteria only, or in combination with conventional methods was found to be effective in some experimental models of cancer (tumor regression and increased survival rate). In this article, we reviewed the major advantages, challenges, and prospective directions for combinations of bacteria with conventional methods for tumor therapy.
Identifiants
pubmed: 30950210
doi: 10.1002/cam4.2148
pmc: PMC6558487
doi:
Substances chimiques
Bacterial Toxins
0
Enzymes
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3167-3181Subventions
Organisme : NIAID NIH HHS
ID : R01 AI050875
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI121700
Pays : United States
Informations de copyright
© 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.
Références
Front Oncol. 2017 Apr 18;7:64
pubmed: 28459041
Biochem Biophys Res Commun. 2007 Dec 28;364(4):985-9
pubmed: 17971292
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8668-73
pubmed: 23610422
Zentralbl Bakteriol Orig A. 1979 Mar;243(1):102-12
pubmed: 442877
EMBO J. 1997 Jan 15;16(2):281-94
pubmed: 9029149
Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15155-60
pubmed: 11724950
Nat Protoc. 2006;1(6):2988-94
pubmed: 17406559
Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3814-8
pubmed: 8170993
Cancer Treat Res. 2002;112:1-26
pubmed: 12481709
Nutrition. 2014 Apr;30(4):495-6
pubmed: 24607309
Ann Transl Med. 2015 May;3(Suppl 1):S21
pubmed: 26046067
IDrugs. 2010 Oct;13(10):701-6
pubmed: 20878592
Br J Cancer. 2003 Nov 3;89(9):1796-801
pubmed: 14583786
Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):755-60
pubmed: 15644448
Proc Natl Acad Sci U S A. 1975 Sep;72(9):3666-70
pubmed: 1103152
J Cell Physiol. 2018 Mar;233(3):2019-2031
pubmed: 28198007
Iran J Public Health. 2014 Jul;43(7):1018-9
pubmed: 25909074
Cancer Sci. 2010 Sep;101(9):1925-32
pubmed: 20579076
Methods Mol Med. 2000;35:419-36
pubmed: 21390821
Br J Cancer. 2007 Mar 12;96(5):758-61
pubmed: 17311022
Clin Cancer Res. 2009 Aug 15;15(16):5170-7
pubmed: 19671860
Am J Pathol. 2004 May;164(5):1627-33
pubmed: 15111309
J Korean Med Sci. 2014 Oct;29(10):1372-8
pubmed: 25368490
Nat Med. 2003 Dec;9(12):1465-6
pubmed: 14647523
J Clin Invest. 2004 Mar;113(5):774-83
pubmed: 14991076
Clin Cancer Res. 2005 Jul 1;11(13):4827-34
pubmed: 16000580
Cancer Discov. 2012 Jul;2(7):624-37
pubmed: 22728436
Cancer Biol Ther. 2007 Sep;6(9):1449-54
pubmed: 17881902
Microb Biotechnol. 2017 Sep;10(5):1074-1078
pubmed: 28771926
Transl Oncol. 2018 Apr;11(2):330-337
pubmed: 29425952
Environ Health Perspect. 1995 Nov;103 Suppl 8:263-8
pubmed: 8741796
Immunol Res. 2008;42(1-3):233-45
pubmed: 19018479
J Clin Oncol. 2000 Oct 1;18(19):3339-45
pubmed: 11013273
Cancer Res. 2005 May 1;65(9):3920-7
pubmed: 15867392
Am J Gastroenterol. 2002 Aug;97(8):2150-2
pubmed: 12190202
Front Biosci. 2007 May 01;12:3880-91
pubmed: 17485344
Integr Cancer Ther. 2018 Dec;17(4):1027-1047
pubmed: 30136590
Pharmacol Res. 2016 Dec;114:56-66
pubmed: 27771464
Int J Cancer. 2007 Aug 1;121(3):666-74
pubmed: 17397027
Cancer Gene Ther. 2003 Oct;10(10):737-44
pubmed: 14502226
Nano Lett. 2016 Jun 8;16(6):3493-9
pubmed: 27148804
Eur J Cancer. 2000 Dec;36(18):2397-402
pubmed: 11094316
Cancer Res. 1997 Oct 15;57(20):4537-44
pubmed: 9377566
Eur J Cancer. 2007 Feb;43(3):490-6
pubmed: 17113280
N Engl J Med. 2001 Jan 4;344(1):30-7
pubmed: 11136958
Med Hypotheses. 2015 Mar;84(3):194-8
pubmed: 25613566
Appl Environ Microbiol. 1999 Oct;65(10):4295-300
pubmed: 10508051
Nat Commun. 2018 Apr 26;9(1):1680
pubmed: 29700283
Cytokine. 2017 Jan;89:160-172
pubmed: 26778055
Br J Cancer. 1999 Aug;80(11):1726-33
pubmed: 10468288
Magn Reson Med. 2008 Jun;59(6):1225-31
pubmed: 18506784
Chonnam Med J. 2016 Sep;52(3):173-84
pubmed: 27689027
Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):646-50
pubmed: 24054874
Cancer Res. 1955 Aug;15(7):473-8
pubmed: 13240693
Carcinogenesis. 2010 Jan;31(1):100-10
pubmed: 19934210
FEMS Microbiol Lett. 2005 May 1;246(1):67-73
pubmed: 15869963
Nucl Med Mol Imaging. 2017 Jun;51(2):118-126
pubmed: 28559936
Nat Rev Microbiol. 2012 Oct;10(10):705-15
pubmed: 22941504
Breast Cancer Res Treat. 2001 Mar;66(2):165-70
pubmed: 11437103
Clin Cancer Res. 2003 Jun;9(6):1957-71
pubmed: 12796357
Cancer Sci. 2007 Jul;98(7):1107-12
pubmed: 17498202
J Biol Chem. 2000 Feb 11;275(6):4363-8
pubmed: 10660606
Nat Biomed Eng. 2018 Jan;2(1):27-37
pubmed: 31015663
Drug Discov Today. 2012 Sep;17(17-18):928-34
pubmed: 22484464
Radiat Oncol. 2010 May 05;5:31
pubmed: 20444243
Radiat Res. 2001 May;155(5):716-23
pubmed: 11302769
Adv Drug Deliv Rev. 2010 Aug 30;62(11):1064-79
pubmed: 20691229
Mol Ther. 2010 Mar;18(3):635-42
pubmed: 20051939
Cell Biochem Biophys. 2014 Jun;69(2):357-61
pubmed: 24366547
Methods Enzymol. 2009;465:251-65
pubmed: 19913171
Gene Ther. 2001 Aug;8(15):1197-201
pubmed: 11509951
Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):228-34
pubmed: 22000579
Lancet Oncol. 2000 Oct;1:86-93
pubmed: 11905673
Cancer Res. 2010 Jan 1;70(1):18-23
pubmed: 20028866
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Jun;265(1-2):33-44
pubmed: 3673337
Expert Opin Investig Drugs. 2007 Feb;16(2):209-18
pubmed: 17243940
Cell. 2006 Apr 21;125(2):385-98
pubmed: 16630824
Clin Cancer Res. 2001 Nov;7(11):3314-24
pubmed: 11705842
Infect Agent Cancer. 2018 Mar 15;13:9
pubmed: 29568324
Cancer Sci. 2003 Dec;94(12):1021-8
pubmed: 14662015
Diagn Microbiol Infect Dis. 1989 Jul-Aug;12(4 Suppl):201S-207S
pubmed: 2686921
Science. 2008 Apr 11;320(5873):226-30
pubmed: 18403709
Nat Biotechnol. 1999 Jan;17(1):37-41
pubmed: 9920266
Mol Imaging Biol. 2008 Jan-Feb;10(1):54-61
pubmed: 17994265
Eur J Cancer. 2012 Apr;48(6):875-81
pubmed: 21741230
Trends Microbiol. 2005 Mar;13(3):103-10
pubmed: 15737728
Nutrition. 2006 Feb;22(2):179-86
pubmed: 16459231
J Clin Oncol. 2002 Jan 1;20(1):142-52
pubmed: 11773163
Oncologist. 2002;7(6):492-508
pubmed: 12490737
Toxicol Sci. 2005 Dec;88(2):562-75
pubmed: 16162850
Cochrane Database Syst Rev. 2018 Aug 31;8:CD008831
pubmed: 30168576
Biochem Biophys Res Commun. 2015 Dec 18;468(3):463-70
pubmed: 26271592
Anticancer Res. 2001 Mar-Apr;21(2A):857-61
pubmed: 11396175
Br J Cancer. 2006 Nov 6;95(9):1212-9
pubmed: 17024128
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15083-8
pubmed: 14657371
Drug Des Devel Ther. 2013 May 03;7:375-88
pubmed: 23667309
J Immunother. 2003 Mar-Apr;26(2):179-80
pubmed: 12616110
J Biomed Sci. 2010 Mar 23;17(1):21
pubmed: 20331869
Trends Mol Med. 2017 Jul;23(7):580-582
pubmed: 28583420
Nat Protoc. 2008;3(4):629-36
pubmed: 18388945
Nat Rev Microbiol. 2018 Apr;16(4):214-225
pubmed: 29398705
Cell Biochem Biophys. 2015 Jul;72(3):757-69
pubmed: 27352189
Toxicol Pathol. 1999 Jan-Feb;27(1):53-7
pubmed: 10367674
Nat Biotechnol. 2004 Mar;22(3):313-20
pubmed: 14990953
Cancer Biol Ther. 2009 Mar 15;8(6):505-11
pubmed: 19305160
Pharmacol Res. 2016 Mar;105:164-75
pubmed: 26826398
CA Cancer J Clin. 2017 Jul 8;67(4):326-344
pubmed: 28481406
Gene Ther Mol Biol. 2009;13(A):15-19
pubmed: 19503758
Exp Anim. 2016 Nov 1;65(4):413-418
pubmed: 27301721
Toxins (Basel). 2017 Jul 28;9(8):
pubmed: 28788054
Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):1213-9
pubmed: 18243569
Biotechnol Bioeng. 2006 Jul 5;94(4):710-21
pubmed: 16470601
Cancer Gene Ther. 2001 Apr;8(4):294-7
pubmed: 11393282
J Gene Med. 2018 May;20(5):e3015
pubmed: 29575374
Complement Ther Med. 2013 Dec;21(6):712-23
pubmed: 24280481
Br J Cancer. 2009 Nov 17;101(10):1683-91
pubmed: 19861961
J Control Release. 2001 Jul 6;74(1-3):313-5
pubmed: 11489512
Nat Rev Microbiol. 2003 Dec;1(3):237-42
pubmed: 15035028
Br J Cancer. 2007 Oct 22;97(8):1028-34
pubmed: 17895895
Trends Microbiol. 2006 Apr;14(4):190-6
pubmed: 16500103
Anticancer Res. 2002 Nov-Dec;22(6A):3261-6
pubmed: 12530073
Br J Nutr. 2013 Feb 14;109(3):457-66
pubmed: 22874095
Gene Ther. 2009 Mar;16(3):329-39
pubmed: 19177133
Zentralbl Bakteriol Mikrobiol Hyg A. 1988 May;268(3):347-56
pubmed: 3043982
Front Microbiol. 2018 Jan 23;9:16
pubmed: 29472896
Science. 2006 Nov 24;314(5803):1308-11
pubmed: 17124324
CA Cancer J Clin. 2015 Mar;65(2):87-108
pubmed: 25651787
Life (Basel). 2012 Dec 27;3(1):1-20
pubmed: 25371329
PLoS One. 2017 Jun 29;12(6):e0180034
pubmed: 28662099
Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15172-7
pubmed: 15471990
Nat Rev Cancer. 2010 Nov;10(11):785-94
pubmed: 20944664
Front Microbiol. 2018 May 15;9:983
pubmed: 29867884
Curr Opin Clin Nutr Metab Care. 1999 Sep;2(5):405-11
pubmed: 10589383
J Clin Invest. 2000 May;105(9):1161-7
pubmed: 10791987
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Strahlentherapie. 1977 Apr;153(4):263-6
pubmed: 857352
Cancer Med. 2019 Jun;8(6):3167-3181
pubmed: 30950210
Strahlentherapie. 1976 Dec;152(6):537-41
pubmed: 1006715
Biomed Pharmacother. 2018 May;101:929-937
pubmed: 29635902
Exp Cell Res. 1998 Jul 10;242(1):341-50
pubmed: 9665831
Cancer Treat Rev. 2015 Nov;41(9):742-53
pubmed: 26051911
J Surg Res. 2010 Dec;164(2):248-55
pubmed: 19766244
Mol Microbiol. 1999 Mar;31(6):1631-41
pubmed: 10209738
Oncoimmunology. 2017 Oct 16;7(2):e1382791
pubmed: 29308303
Cancer Biol Ther. 2004 Mar;3(3):326-37
pubmed: 14739784
Cell. 2003 Oct 3;115(1):25-35
pubmed: 14532000
Mol Ther. 2005 May;11(5):707-16
pubmed: 15851009
Med Hypotheses. 2018 Oct;119:37-40
pubmed: 30122489
Nat Rev Cancer. 2018 Dec;18(12):727-743
pubmed: 30405213
Curr Opin Drug Discov Devel. 2002 Mar;5(2):194-9
pubmed: 11926125
Int J Cancer. 2010 Jun 1;126(11):2622-34
pubmed: 19824039
World J Gastroenterol. 2007 Feb 14;13(6):912-5
pubmed: 17352022
JPEN J Parenter Enteral Nutr. 2009 Sep-Oct;33(5):569-70
pubmed: 19423769
Nat Nanotechnol. 2014 Apr;9(4):311-6
pubmed: 24633522