The low-profile Neuroform Atlas stent in the treatment of wide-necked intracranial aneurysms - immediate and midterm results: An Italian multicenter registry.


Journal

Journal of neuroradiology = Journal de neuroradiologie
ISSN: 0150-9861
Titre abrégé: J Neuroradiol
Pays: France
ID NLM: 7705086

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 19 10 2018
revised: 22 01 2019
accepted: 15 03 2019
pubmed: 6 4 2019
medline: 6 7 2021
entrez: 6 4 2019
Statut: ppublish

Résumé

Wide-necked brain aneurysms therapy remains a challenge for neurointerventionalists, mainly for the high recurrence rate. Low-profile stents make feasible the treatment of these aneurysms. In our multicenter series we analyzed clinical and angiographic results of Neuroform Atlas stent-assisted coiling. From January 2016 to March 2017, 113 wide-necked aneurysms were discovered with CTA, MRA and DSA. The Atlas stent-assisted coiling procedures were performed under general anesthesia with sequential or jailing techniques. Six months follow-up DSA was performed to assess the recurrence rate through the modified Raymond-Roy occlusion scale (RROC). Moreover, patients were evaluated clinically to analyse the degree of disability according to the mRS. MRI was performed at 12 months evaluating both the cerebral tissue and the vessels. In all the procedures it was feasible to navigate the Neuroform Atlas to the goal vessel and deploy the stent across the aneurysmal neck. Intra-procedural complications account for the 6.2% (7/113). The immediate occlusion rate was RROC 1 in 88%, 2 in 9% and 3 in 3% of cases. The 6 months clinical data showed mRS Score 0-1 in 96.5% of patients; 3 patients died of complications related to SAH. The 12 months follow-up showed RROC of 1 in 82%, 2 in 13% and 3 in 5% of cases. No aneurysm has been retreated. In our multicenter experience the Neuroform Atlas stent assisted-coiling has shown to be a safe and effective technique for the treatment of wide-necked intracranial aneurysms with encouraging clinical and angiographic results.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Wide-necked brain aneurysms therapy remains a challenge for neurointerventionalists, mainly for the high recurrence rate. Low-profile stents make feasible the treatment of these aneurysms. In our multicenter series we analyzed clinical and angiographic results of Neuroform Atlas stent-assisted coiling.
MATERIALS AND METHODS METHODS
From January 2016 to March 2017, 113 wide-necked aneurysms were discovered with CTA, MRA and DSA. The Atlas stent-assisted coiling procedures were performed under general anesthesia with sequential or jailing techniques. Six months follow-up DSA was performed to assess the recurrence rate through the modified Raymond-Roy occlusion scale (RROC). Moreover, patients were evaluated clinically to analyse the degree of disability according to the mRS. MRI was performed at 12 months evaluating both the cerebral tissue and the vessels.
RESULTS RESULTS
In all the procedures it was feasible to navigate the Neuroform Atlas to the goal vessel and deploy the stent across the aneurysmal neck. Intra-procedural complications account for the 6.2% (7/113). The immediate occlusion rate was RROC 1 in 88%, 2 in 9% and 3 in 3% of cases. The 6 months clinical data showed mRS Score 0-1 in 96.5% of patients; 3 patients died of complications related to SAH. The 12 months follow-up showed RROC of 1 in 82%, 2 in 13% and 3 in 5% of cases. No aneurysm has been retreated.
CONCLUSIONS CONCLUSIONS
In our multicenter experience the Neuroform Atlas stent assisted-coiling has shown to be a safe and effective technique for the treatment of wide-necked intracranial aneurysms with encouraging clinical and angiographic results.

Identifiants

pubmed: 30951769
pii: S0150-9861(18)30391-2
doi: 10.1016/j.neurad.2019.03.005
pii:
doi:

Substances chimiques

Platelet Aggregation Inhibitors 0

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

421-427

Informations de copyright

Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Auteurs

Antonio A Caragliano (AA)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy. Electronic address: caraglia1987@gmail.com.

Rosario Papa (R)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.

Antonio Pitrone (A)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.

Nicola Limbucci (N)

Neurovascular Interventional Unit, Careggi University Hospital, Florence, Italy.

Sergio Nappini (S)

Neurovascular Interventional Unit, Careggi University Hospital, Florence, Italy.

Maria Ruggiero (M)

Neuroradiology Unit, AUSL Romagna, Cesena, Italy.

Emiliano Visconti (E)

Neuroradiology Unit, AUSL Romagna, Cesena, Italy.

Andrea Alexandre (A)

Institute of Radiology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.

Roberto Menozzi (R)

Neurovascular Interventional Unit, AOU Parma, Parma, Italy.

Dario Lauretti (D)

Neuroradiology Unit, Department of translation research and new technologies in medicine and surgery, University of Pisa, Pisa, Italy.

Nicola Cavasin (N)

Neuroradiology Unit, Department of Radiology, Ospedale dell'Angelo, Mestre, Venezia, Italy.

Angela Alibrandi (A)

Department of Economics, Unit of Statistical and Mathematical Sciences, AOU Policlinico G. Martino, Messina, Italy.

Agostino Tessitore (A)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.

Marcello Longo (M)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.

Sergio L Vinci (SL)

Neuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.

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