Successful resection of pancreatic metastasis from oesophageal squamous cell carcinoma: a case report and review of the literature.
Aged, 80 and over
Chemoradiotherapy, Adjuvant
Endosonography
Esophageal Neoplasms
/ diagnostic imaging
Esophageal Squamous Cell Carcinoma
/ diagnostic imaging
Esophagectomy
Female
Humans
Lymph Node Excision
Lymph Nodes
/ diagnostic imaging
Lymphatic Metastasis
/ diagnostic imaging
Neoplasm Recurrence, Local
/ diagnostic imaging
Pancreas
/ diagnostic imaging
Pancreatectomy
Pancreatic Neoplasms
/ diagnostic imaging
Splenectomy
Tomography, X-Ray Computed
Treatment Outcome
Isolated metastasis
Oesophageal cancer
Pancreas
Pancreatic metastasis
Journal
BMC cancer
ISSN: 1471-2407
Titre abrégé: BMC Cancer
Pays: England
ID NLM: 100967800
Informations de publication
Date de publication:
05 Apr 2019
05 Apr 2019
Historique:
received:
15
09
2018
accepted:
28
03
2019
entrez:
7
4
2019
pubmed:
7
4
2019
medline:
21
8
2019
Statut:
epublish
Résumé
Oesophageal cancer has a high metastatic potential and poor prognosis, with a significant risk of recurrence after radical resection. However, resected pancreatic metastasis from oesophageal cancer is rare. Eleven years prior, a seventy-year-old woman had been treated with transthoracic radical oesophagectomy for oesophageal squamous cell carcinoma. Four years prior, she had undergone chemotherapy for lymph node recurrence at the splenic hilum and achieved a partial response. She had also received chemoradiotherapy for lymph node recurrence at the splenic hilum 3 years prior; a complete response was achieved. However, routine follow-up with abdominal computed tomography recently revealed a tumour at the pancreatic tail and swollen lymph nodes. The patient underwent distal pancreatectomy on the basis of a pre-operative diagnosis of primary pancreatic cancer, although a histological examination of the surgical specimen revealed metastatic squamous cell carcinoma that was compatible with metachronous pancreatic metastasis from oesophageal squamous cell carcinoma. The patient has been undergoing clinical follow-up without adjuvant therapy and has been disease-free for 24 months after resection of the pancreatic metastasis. Resection of pancreatic metastasis may improve prognosis and should be considered when treating patients with solitary metastasis from oesophageal squamous cell carcinoma.
Sections du résumé
BACKGROUND
BACKGROUND
Oesophageal cancer has a high metastatic potential and poor prognosis, with a significant risk of recurrence after radical resection. However, resected pancreatic metastasis from oesophageal cancer is rare.
CASE PRESENTATION
METHODS
Eleven years prior, a seventy-year-old woman had been treated with transthoracic radical oesophagectomy for oesophageal squamous cell carcinoma. Four years prior, she had undergone chemotherapy for lymph node recurrence at the splenic hilum and achieved a partial response. She had also received chemoradiotherapy for lymph node recurrence at the splenic hilum 3 years prior; a complete response was achieved. However, routine follow-up with abdominal computed tomography recently revealed a tumour at the pancreatic tail and swollen lymph nodes. The patient underwent distal pancreatectomy on the basis of a pre-operative diagnosis of primary pancreatic cancer, although a histological examination of the surgical specimen revealed metastatic squamous cell carcinoma that was compatible with metachronous pancreatic metastasis from oesophageal squamous cell carcinoma. The patient has been undergoing clinical follow-up without adjuvant therapy and has been disease-free for 24 months after resection of the pancreatic metastasis.
CONCLUSIONS
CONCLUSIONS
Resection of pancreatic metastasis may improve prognosis and should be considered when treating patients with solitary metastasis from oesophageal squamous cell carcinoma.
Identifiants
pubmed: 30953505
doi: 10.1186/s12885-019-5549-9
pii: 10.1186/s12885-019-5549-9
pmc: PMC6451211
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Pagination
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