Effect of alpha-lipoic acid at the combination with mefenamic acid in girls with primary dysmenorrhea: randomized, double-blind, placebo-controlled clinical trial.


Journal

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN: 1473-0766
Titre abrégé: Gynecol Endocrinol
Pays: England
ID NLM: 8807913

Informations de publication

Date de publication:
Sep 2019
Historique:
pubmed: 9 4 2019
medline: 22 1 2020
entrez: 9 4 2019
Statut: ppublish

Résumé

Primary dysmenorrhea is a common gynecologic disorder and is one of the main causes for referral to the gynecology clinic. This study aimed to determine the effects of alpha-lipoic acid (ALA) and mefenamic acid and a combination compared with placebo on the girls with primary dysmenorrhea. This double-blind, placebo-controlled clinical trial done on population consisted of female students living in dormitories of Qazvin University of Medical Sciences who had moderate to severe dysmenorrhea using the Visual Analog Scale (VAS) questionnaire. Participants were randomly divided into four groups (

Identifiants

pubmed: 30957578
doi: 10.1080/09513590.2019.1590544
doi:

Substances chimiques

Placebos 0
Mefenamic Acid 367589PJ2C
Thioctic Acid 73Y7P0K73Y

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

782-786

Auteurs

Mojgan Yousefi (M)

a Student Research Committee, School of Health, Qazvin University of Medical Sciences , Qazvin , Iran.
b Metabolic Diseases Research Center, Qazvin University of Medical Sciences , Qazvin , Iran.

Maria Kavianpour (M)

c Department of Tissue Engineering and Applied Cell Sciences, Faculty of Advanced Technologies in Medicine, Tehran University of Medical Sciences , Tehran , Iran.

Sepideh Hesami (S)

a Student Research Committee, School of Health, Qazvin University of Medical Sciences , Qazvin , Iran.
b Metabolic Diseases Research Center, Qazvin University of Medical Sciences , Qazvin , Iran.

Mohamadreza Rashidi Nooshabadi (M)

d Department of Pharmacology, School of Medicine, Qom University of Medical Sciences , Qom , Iran.

Hossein Khadem Haghighian (H)

a Student Research Committee, School of Health, Qazvin University of Medical Sciences , Qazvin , Iran.
b Metabolic Diseases Research Center, Qazvin University of Medical Sciences , Qazvin , Iran.

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Classifications MeSH