Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80.


Journal

European journal of clinical nutrition
ISSN: 1476-5640
Titre abrégé: Eur J Clin Nutr
Pays: England
ID NLM: 8804070

Informations de publication

Date de publication:
01 2020
Historique:
received: 13 06 2018
accepted: 26 03 2019
revised: 26 03 2019
pubmed: 10 4 2019
medline: 25 6 2021
entrez: 10 4 2019
Statut: ppublish

Résumé

The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. We prospectively followed 8925 participants (3916 men and 5009 women) aged 30-79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47-0.87; P Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

Sections du résumé

BACKGROUND/OBJECTIVES
The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population.
SUBJECTS/METHODS
We prospectively followed 8925 participants (3916 men and 5009 women) aged 30-79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables.
RESULTS
During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47-0.87; P
CONCLUSIONS
Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

Identifiants

pubmed: 30962516
doi: 10.1038/s41430-019-0424-y
pii: 10.1038/s41430-019-0424-y
doi:

Substances chimiques

Carbohydrates 0
Dietary Fiber 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

67-76

Références

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Auteurs

Itsuko Miyazawa (I)

Department of Medicine, Shiga University of Medical Science, Otsu, 520-2192, Japan. shimojo@belle.shiga-med.ac.jp.

Katsuyuki Miura (K)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, 520-2192, Japan.

Naoko Miyagawa (N)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.
International Center for Nutrition and Information, National Institute of Biomedical Innovation, Health and Nutrition, Tokyo, 162-8636, Japan.

Keiko Kondo (K)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.

Aya Kadota (A)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, 520-2192, Japan.

Nagako Okuda (N)

Department of Health and Nutrition, University of Human Arts and Sciences, Saitama, 339-8539, Japan.

Akira Fujiyoshi (A)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Department of Hygiene, School of Medicine Wakayama Medical University, Wakayama, 641-8509, Japan.

Izumi Chihara (I)

Department of Public Health, Jichi Medical University, Shimotsuke, 329-0498, Japan.

Yosikazu Nakamura (Y)

Department of Public Health, Jichi Medical University, Shimotsuke, 329-0498, Japan.

Atsushi Hozawa (A)

Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan.

Yasuyuki Nakamura (Y)

Department of Food Science and Human Nutrition, Faculty of Agriculture, Ryukoku University, Otsu, 520-2194, Japan.

Yoshikuni Kita (Y)

Science of Nursing, Tsuruga Nursing University, Tsuruga, 914-0814, Japan.

Katsushi Yoshita (K)

Department of Food Science and Nutrition, Graduate School of Human Life Science, Osaka City University, Osaka, 558-8585, Japan.

Tomonori Okamura (T)

Department of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, 160-8582, Japan.

Akira Okayama (A)

Research Institute of Strategy for Prevention, Tokyo, 104-0033, Japan.

Hirotsugu Ueshima (H)

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.
Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, 520-2192, Japan.

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