Towards an improved access to psychiatric rehabilitation: availability and effectiveness at 1-year follow-up of psychoeducation, cognitive remediation therapy, cognitive behaviour therapy and social skills training in the FondaMental Advanced Centers of Expertise-Schizophrenia (FACE-SZ) national cohort.
Effectiveness
Functioning
Psychosocial interventions
Rehabilitation
Schizophrenia
Journal
European archives of psychiatry and clinical neuroscience
ISSN: 1433-8491
Titre abrégé: Eur Arch Psychiatry Clin Neurosci
Pays: Germany
ID NLM: 9103030
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
05
12
2018
accepted:
21
03
2019
pubmed:
10
4
2019
medline:
10
1
2020
entrez:
10
4
2019
Statut:
ppublish
Résumé
Psychosocial Interventions (PIs) have shown positive effects on clinical and functional outcomes of schizophrenia (SZ) in randomized controlled trials. However their effectiveness and accessibility remain unclear to date in "real world" schizophrenia. The objectives of the present study were (i) to assess the proportion of SZ outpatients who benefited from PIs between 2010 and 2015 in France after an Expert Center Intervention in a national multicentric non-selected community-dwelling sample; (ii) to assess PIs' effectiveness at 1-year follow-up. 183 SZ outpatients were recruited from FondaMental Advanced Centers of Expertise for Schizophrenia cohort. Baseline and 1-year evaluations included sociodemographic data, current treatments, illness characteristics and standardized scales for clinical severity, adherence to treatment, quality of life, a large cognitive battery, and daily functioning assessment. Only 7 (3.8%) received a PI before the evaluation, and 64 (35%) have received at least one PI during the 1-year follow-up. Having had at least one PI during the follow-up has been associated in multivariate analyses with significantly higher improvement in positive and negative symptoms (respectively p =0.031; p = 0.011), mental flexibility (TMT B, p = 0.029; C-VF, p = 0.02) and global functioning (p =0.042). CBT and SST were associated with higher cognitive improvements, while CRT was associated with clinical improvement. These results have not been demonstrated before and suggest that the effect of each PI is larger than its initial target. The present study has confirmed the PIs' effectiveness in a large sample of community-dwelling SZ outpatients at 1 year follow-up. Efforts to improve access to PI should be reinforced in public health policies.
Identifiants
pubmed: 30963264
doi: 10.1007/s00406-019-01001-4
pii: 10.1007/s00406-019-01001-4
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
599-610Subventions
Organisme : Agence Nationale de la Recherche
ID : ANR-11-IDEX-0004-02
Organisme : Agence Nationale de la Recherche
ID : ANR-10-COHO-10-01
Investigateurs
M Andrianarisoa
(M)
B Aouizerate
(B)
N Bazin
(N)
F Berna
(F)
O Blanc
(O)
L Brunel
(L)
E Bulzacka
(E)
D Capdevielle
(D)
I Chereau-Boudet
(I)
G Chesnoy-Servanin
(G)
N Coulon
(N)
J M Danion
(JM)
T D'Amato
(T)
A Deloge
(A)
H Denizot
(H)
J M Dorey
(JM)
C Dubertret
(C)
J Dubreucq
(J)
C Faget
(C)
C Fluttaz
(C)
G Fond
(G)
S Fonteneau
(S)
F Gabayet
(F)
E Giraud-Baro
(E)
M Jaroir
(M)
D Lacelle
(D)
C Lançon
(C)
H Laouamri
(H)
M Leboyer
(M)
T Le Gloahec
(T)
S Leignier
(S)
Y Le Strat
(Y)
P M Llorca
(PM)
J Mallet
(J)
E Metairie
(E)
D Misdrahi
(D)
I Offerlin-Meyer
(I)
C Passerieux
(C)
P Peri
(P)
C C Perier
(CC)
S Pires
(S)
C Portalier
(C)
L Ramet
(L)
R Rey
(R)
C Roman
(C)
A Schandrin
(A)
F Schurhoff
(F)
A Tessier
(A)
A M Tronche
(AM)
M Urbach
(M)
F Vaillant
(F)
A Vehier
(A)
P Vidailhet
(P)
E Vilà
(E)
H Yazbek
(H)
A Zinetti-Bertschy
(A)
Références
Schizophr Res. 2000 May 5;42(3):241-7
pubmed: 10785582
Br J Clin Psychol. 2002 Nov;41(Pt 4):417-22
pubmed: 12437796
Acta Psychiatr Scand Suppl. 2003;(416):16-23
pubmed: 12755850
Schizophr Res. 2003 Sep 1;63(1-2):137-49
pubmed: 12892868
Encephale. 2005 Jan-Feb;31(1 Pt 1):31-43
pubmed: 15971638
Schizophr Bull. 2006 Oct;32(4):765-75
pubmed: 16844723
Schizophr Bull. 2008 May;34(3):523-37
pubmed: 17962231
Am J Psychiatry. 2007 Dec;164(12):1791-802
pubmed: 18056233
Schizophr Res. 2008 Mar;100(1-3):60-9
pubmed: 18255269
J Consult Clin Psychol. 2008 Jun;76(3):491-504
pubmed: 18540742
Encephale. 2010 Oct;36(5):397-407
pubmed: 21035630
Schizophr Res. 2011 Feb;125(2-3):284-90
pubmed: 21094025
Am J Psychiatry. 2011 May;168(5):472-85
pubmed: 21406461
Schizophr Res. 2011 Sep;131(1-3):133-8
pubmed: 21669512
Schizophr Bull. 2011 Sep;37 Suppl 2:S71-9
pubmed: 21860050
Am J Psychiatry. 2012 Jul;169(7):710-8
pubmed: 22581070
Psychiatry Res. 2012 Dec 30;200(2-3):102-7
pubmed: 22769048
J Clin Psychiatry. 2012 Sep;73(9):1212-9
pubmed: 22939029
Schizophr Bull. 2013 Nov;39(6):1296-306
pubmed: 23172003
Schizophr Res. 2013 Jun;147(1):68-74
pubmed: 23583327
Biol Psychiatry. 2013 May 15;73(10):935-7
pubmed: 23628236
Schizophr Res. 2013 Oct;150(1):58-63
pubmed: 23993864
Psychosis. 2013 Jan 1;5(3):null
pubmed: 24187582
J Ment Health. 2014 Aug;23(4):162-5
pubmed: 24433132
Can J Psychiatry. 2014 Jan;59(1):5-12
pubmed: 24444318
World Psychiatry. 2014 Feb;13(1):12-20
pubmed: 24497237
Schizophr Res. 2014 Aug;157(1-3):99-106
pubmed: 24972754
Can J Psychiatry. 2014 Apr;59(4):178-86
pubmed: 25007110
Schizophr Res. 2015 Mar;162(1-3):35-41
pubmed: 25640526
Front Psychiatry. 2015 Apr 28;6:66
pubmed: 25972817
Eur Psychiatry. 2015 Sep;30(6):728-35
pubmed: 26072427
Psychol Psychother. 2016 Sep;89(3):324-50
pubmed: 26537838
Psychiatry Res. 2016 Oct 30;244:145-50
pubmed: 27479105
Clin Psychol Rev. 2017 Mar;52:43-51
pubmed: 27930934
Schizophr Res. 2018 Jan 30;:null
pubmed: 29395609
BMC Psychol. 2018 Jul 17;6(1):32
pubmed: 30016999
Psychiatry Res. 1988 Nov;26(2):223-38
pubmed: 3237915
Schizophr Bull. 1987;13(2):261-76
pubmed: 3616518
Acta Psychiatr Scand. 1994 Jan;89(1):62-7
pubmed: 7908156
Br J Psychiatry Suppl. 1993 Dec;(22):39-44
pubmed: 8110442