Early in life effects and heredity: reconciling neo-Darwinism with neo-Lamarckism under the banner of the inclusive evolutionary synthesis.
Weismann barrier
epigenetics
inclusive evolutionary synthesis
modern synthesis
timescales
Journal
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
ISSN: 1471-2970
Titre abrégé: Philos Trans R Soc Lond B Biol Sci
Pays: England
ID NLM: 7503623
Informations de publication
Date de publication:
15 04 2019
15 04 2019
Historique:
entrez:
11
4
2019
pubmed:
11
4
2019
medline:
4
3
2020
Statut:
ppublish
Résumé
Recent discoveries show that early in life effects often have long-lasting influences, sometimes even spanning several generations. Such intergenerational effects of early life events appear not easily reconcilable with strict genetic inheritance. However, an integrative evolutionary medicine of early life effects needs a sound view of inheritance in development and evolution. Here, we show how to articulate the gene-centred and non-gene-centred visions of inheritance. We first recall the coexistence of two gene concepts in scientific discussions, a statistical one (focused on patterns of parent-offspring resemblance, and implicitly including non-DNA-sequence-based resemblance), and a molecular one (based on the DNA sequence). We then show how all the different mechanisms of inheritance recently discovered can be integrated into an inclusive theory of evolution where different mechanisms would enable adaptation to changing environments at different timescales. One surprising consequence of this integrative vision of inheritance is that early in life effects start much earlier than fertilization. This article is part of the theme issue 'Developing differences: early-life effects and evolutionary medicine'.
Identifiants
pubmed: 30966884
doi: 10.1098/rstb.2018.0113
pmc: PMC6460090
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20180113Références
Genetics. 2012 Dec;192(4):1447-54
pubmed: 23051642
Mol Ecol. 2017 Sep;26(17):4364-4377
pubmed: 28626971
Trends Endocrinol Metab. 2010 Apr;21(4):214-22
pubmed: 20074974
Reprod Toxicol. 2011 Apr;31(3):337-43
pubmed: 21055462
BJOG. 2008 Sep;115(10):1243-9
pubmed: 18715409
Genetics. 2011 Aug;188(4):1015-7
pubmed: 21596900
Nature. 2006 Aug 24;442(7105):882
pubmed: 16929289
Science. 1969 May 16;164(3881):788-98
pubmed: 5767777
Philos Trans R Soc Lond B Biol Sci. 1995 Nov 29;350(1332):133-41
pubmed: 8577857
Neurobiol Dis. 2010 Jul;39(1):61-5
pubmed: 19931614
PLoS One. 2013 May 20;8(5):e61254
pubmed: 23700404
Cell. 2012 Jul 6;150(1):88-99
pubmed: 22738725
J Exp Biol. 2015 Nov;218(Pt 21):3368-73
pubmed: 26347561
Nat Rev Genet. 2011 Jun 17;12(7):475-86
pubmed: 21681209
Mol Biol Evol. 2017 Sep 1;34(9):2285-2306
pubmed: 28535256
J Physiol. 2014 Jun 1;592(11):2307-17
pubmed: 24882815
Development. 2003 Dec;130(24):5869-84
pubmed: 14597570
Int J Epidemiol. 2014 Aug;43(4):989-1000
pubmed: 24691957
Genetics. 2010 Apr;184(4):1037-50
pubmed: 20100941
Science. 2016 Jan 22;351(6271):397-400
pubmed: 26721680
AJS. 2004 May;109(6):1500-6
pubmed: 15307257
J Exp Biol. 2006 Jun;209(Pt 12):2362-7
pubmed: 16731812
J Hist Biol. 2019 Dec;52(4):509-518
pubmed: 31620957
Proc Biol Sci. 2015 Jul 22;282(1811):
pubmed: 26136447
Br Med Bull. 2001;60:5-20
pubmed: 11809615
Bioessays. 2013 Jun;35(6):571-8
pubmed: 23580343
Nature. 1988 Sep 8;335(6186):142-5
pubmed: 3045565
Nat Neurosci. 2014 Jan;17(1):89-96
pubmed: 24292232
Nat Rev Genet. 2012 Jan 31;13(3):153-62
pubmed: 22290458
Science. 2016 Jan 22;351(6271):391-396
pubmed: 26721685
J Physiol. 2015 May 1;593(9):2243
pubmed: 25931410
Proc Biol Sci. 2001 Mar 22;268(1467):647-50
pubmed: 11297183
Biol Rev Camb Philos Soc. 2017 Nov;92(4):2084-2111
pubmed: 28220606
Trends Ecol Evol. 2013 Jun;28(6):351-8
pubmed: 23540765
Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2133-8
pubmed: 25646479
Nature. 2014 Oct 9;514(7521):161-4
pubmed: 25297418
Circ Res. 2012 Feb 3;110(3):483-95
pubmed: 22302755
Cell. 2014 Dec 4;159(6):1352-64
pubmed: 25480298
Evolution. 2012 Aug;66(8):2411-26
pubmed: 22834741
Genetics. 1966 Aug;54(2):595-609
pubmed: 5968643
Ann Surg. 2014 Apr;259(4):642-8
pubmed: 24368636
Philos Rev. 1984;93:335-73
pubmed: 11617920
Hum Mol Genet. 2008 Oct 15;17(R2):R156-65
pubmed: 18852205
Interface Focus. 2017 Oct 6;7(5):20170015
pubmed: 28839929
Curr Opin Plant Biol. 2011 Jun;14(3):267-74
pubmed: 21450514
J Cell Sci. 2008 Jan;121 Suppl 1:1-84
pubmed: 18089652
Philos Trans R Soc Lond B Biol Sci. 2015 Sep 26;370(1678):20140331
pubmed: 26323762
Front Neuroendocrinol. 2008 Jun;29(3):386-97
pubmed: 18462782
Science. 2014 Mar 7;343(6175):1145-8
pubmed: 24505129
Science. 2010 Oct 29;330(6004):622-7
pubmed: 21030646
Science. 1999 Nov 5;286(5442):1155-8
pubmed: 10550053
Nat Neurosci. 2014 Jan;17(1):2-4
pubmed: 24369368
Science. 2013 Nov 8;342(6159):705-6
pubmed: 24202168
J Theor Biol. 1996 Jul 7;181(1):1-9
pubmed: 8796186
Q Rev Biol. 2009 Jun;84(2):131-76
pubmed: 19606595
Nature. 2004 Jul 22;430(6998):419-21
pubmed: 15269759
C R Acad Sci III. 2000 Dec;323(12):1155-65
pubmed: 11147102
Cell. 2007 Feb 23;128(4):655-68
pubmed: 17320504
BJOG. 2013 Apr;120(5):548-53
pubmed: 23346894
Nat Rev Mol Cell Biol. 2013 Oct;14(10):630-42
pubmed: 24026055
J Exp Med. 1944 Feb 1;79(2):137-58
pubmed: 19871359
Nat Rev Genet. 2010 Feb;11(2):137-48
pubmed: 20084086
Acta Biotheor. 2017 Jun;65(2):97-115
pubmed: 28197858
Front Mol Neurosci. 2013 Aug 30;6:24
pubmed: 24009553
PLoS One. 2013;8(3):e59922
pubmed: 23555832
Curr Opin Plant Biol. 2011 Apr;14(2):210-6
pubmed: 21420347
Science. 2011 Oct 21;334(6054):369-73
pubmed: 21921155
PLoS Genet. 2009 Jun;5(6):e1000530
pubmed: 19557164
Nat Rev Genet. 2015 Apr;16(4):213-23
pubmed: 25732611
Evol Dev. 2002 Mar-Apr;4(2):73-5
pubmed: 12004964
Neurosci Biobehav Rev. 2009 Apr;33(4):593-600
pubmed: 18430469
Nature. 2008 Nov 6;456(7218):18-21
pubmed: 18987709
J Evol Biol. 2009 Sep;22(9):1914-22
pubmed: 19702889
Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10513-8
pubmed: 18663219
Nat Rev Genet. 2015 Nov;16(11):641-52
pubmed: 26416311
Nature. 2011 Sep 20;480(7376):245-9
pubmed: 22057020
Science. 2005 Jun 3;308(5727):1466-9
pubmed: 15933200
Proc Biol Sci. 2012 Aug 7;279(1740):2913-21
pubmed: 22593110
Curr Biol. 2010 Oct 26;20(20):R877-8
pubmed: 20971427
Science. 2018 Nov 30;362(6418):1025-1030
pubmed: 30498121
Trends Mol Med. 2015 May;21(5):269-70
pubmed: 25795540
Trends Ecol Evol. 1998 May;13(5):206-10
pubmed: 21238269
Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5942-6
pubmed: 17389367
Genome Res. 2007 Jun;17(6):669-81
pubmed: 17567988
Nat Rev Endocrinol. 2009 Jul;5(7):401-8
pubmed: 19488075
Neurosci Biobehav Rev. 2011 Jun;35(7):1552-61
pubmed: 21458485
Trends Mol Med. 2015 Feb;21(2):134-44
pubmed: 25601643