Skeletal Muscle Hypertrophy, Insulin-like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole-body Resistance Training.
Aging
follistatin
hypertrophy
myostatin
resistance training
sarcopenia
Journal
International journal of preventive medicine
ISSN: 2008-7802
Titre abrégé: Int J Prev Med
Pays: Iran
ID NLM: 101535380
Informations de publication
Date de publication:
2019
2019
Historique:
received:
19
07
2017
accepted:
05
12
2017
entrez:
11
4
2019
pubmed:
11
4
2019
medline:
11
4
2019
Statut:
epublish
Résumé
Sarcopenia describes the inevitable deterioration in muscle mass and strength that accompanies biological aging. The purpose of this study was to investigate the effects of resistance training (RT) on quadriceps hypertrophy and related biochemistry in sarcopenic and healthy elderly men. A total of 31 elderly men (55-70 years old) were classified as sarcopenic and nonsarcopenic and were divided into two groups. Both groups participated in a progressive RT program for 8 weeks. Data indicated that the strength in the sarcopenic group increased more than the healthy group ( The findings from this study suggest that RT improves muscle cross-sectional area and biomarker-related muscle loss in both healthy and sarcopenic elderly men. The findings also demonstrate that growth factor profiles at baseline and changes in testosterone levels play an important role in muscle hypertrophy observed in both groups.
Sections du résumé
BACKGROUND
BACKGROUND
Sarcopenia describes the inevitable deterioration in muscle mass and strength that accompanies biological aging. The purpose of this study was to investigate the effects of resistance training (RT) on quadriceps hypertrophy and related biochemistry in sarcopenic and healthy elderly men.
METHODS
METHODS
A total of 31 elderly men (55-70 years old) were classified as sarcopenic and nonsarcopenic and were divided into two groups. Both groups participated in a progressive RT program for 8 weeks.
RESULTS
RESULTS
Data indicated that the strength in the sarcopenic group increased more than the healthy group (
CONCLUSIONS
CONCLUSIONS
The findings from this study suggest that RT improves muscle cross-sectional area and biomarker-related muscle loss in both healthy and sarcopenic elderly men. The findings also demonstrate that growth factor profiles at baseline and changes in testosterone levels play an important role in muscle hypertrophy observed in both groups.
Identifiants
pubmed: 30967915
doi: 10.4103/ijpvm.IJPVM_310_17
pii: IJPVM-10-29
pmc: PMC6425763
doi:
Types de publication
Journal Article
Langues
eng
Pagination
29Déclaration de conflit d'intérêts
There are no conflicts of interest.
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