Why study inner ear hair cell mitochondria?
Warum sollten die Mitochondrien der Innenohr-Haarzellen untersucht werden?
Cochlea
Deafness
Ototoxic aminoglycoside antibiotics
Vestibular disorders
mtDNA
Journal
HNO
ISSN: 1433-0458
Titre abrégé: HNO
Pays: Germany
ID NLM: 2985099R
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
pubmed:
11
4
2019
medline:
2
7
2019
entrez:
11
4
2019
Statut:
ppublish
Résumé
In several systems of the body (muscle, liver, nerves), new studies have examined the internal structure of mitochondria and brought to light striking new findings about how mitochondria are constructed and how their structure affects cell function. In the inner ear field, however, we have little structural knowledge about hair cell and supporting cell mitochondria, and virtually none about mitochondrial subtypes or how they function in health and disease. The need for such knowledge is discussed in this short review.
Identifiants
pubmed: 30969353
doi: 10.1007/s00106-019-0662-2
pii: 10.1007/s00106-019-0662-2
pmc: PMC8520470
mid: NIHMS1526752
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
429-433Subventions
Organisme : NIDCD NIH HHS
ID : R21 DC013181
Pays : United States
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