Developmental origin, functional maintenance and genetic rescue of osteoclasts.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
10
04
2018
accepted:
06
03
2019
pubmed:
12
4
2019
medline:
18
12
2019
entrez:
12
4
2019
Statut:
ppublish
Résumé
Osteoclasts are multinucleated giant cells that resorb bone, ensuring development and continuous remodelling of the skeleton and the bone marrow haematopoietic niche. Defective osteoclast activity leads to osteopetrosis and bone marrow failure
Identifiants
pubmed: 30971820
doi: 10.1038/s41586-019-1105-7
pii: 10.1038/s41586-019-1105-7
pmc: PMC6910203
mid: NIHMS1052671
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
541-545Subventions
Organisme : NCI NIH HHS
ID : T32 CA009149
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI130345
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL138090
Pays : United States
Organisme : NIA NIH HHS
ID : P01 AG032959
Pays : United States
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