Cell surface cathepsin G can be used as an additional marker to distinguish T cell subsets.
CD39+ Tregs
T regulatory cells
cathepsin G
proteases
Journal
Biomedical reports
ISSN: 2049-9434
Titre abrégé: Biomed Rep
Pays: England
ID NLM: 101613227
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
17
09
2018
accepted:
12
02
2019
entrez:
12
4
2019
pubmed:
12
4
2019
medline:
12
4
2019
Statut:
ppublish
Résumé
The serine protease cathepsin G (CatG) is involved in numerous processes associated with the innate and adaptive immune system. During an immune response, neutrophils secrete CatG, which can bind to the cell surface of immune cells to provoke the proteolytic processing of cytokines and chemokines in order to stimulate lymphocytes. The present study analyzed peripheral blood mononuclear cells to characterize T cell populations in terms of their CatG content by flow cytometry. It was identified that CatG was exclusively present on the cell surface of a subset of T regulatory cells (Tregs), cluster of differentiation (CD) 39
Identifiants
pubmed: 30972220
doi: 10.3892/br.2019.1198
pii: BR-0-0-1198
pmc: PMC6439432
doi:
Types de publication
Journal Article
Langues
eng
Pagination
245-249Références
Eur J Immunol. 2001 Mar;31(3):699-707
pubmed: 11241273
Science. 2004 Mar 5;303(5663):1532-5
pubmed: 15001782
Blood. 2004 Jul 15;104(2):478-86
pubmed: 15044252
J Exp Med. 2006 Jul 10;203(7):1693-700
pubmed: 16818676
Blood. 2007 Aug 15;110(4):1225-32
pubmed: 17449799
J Exp Med. 2007 Jun 11;204(6):1257-65
pubmed: 17502665
Biochimie. 2008 Feb;90(2):227-42
pubmed: 18021746
Purinergic Signal. 2007 Mar;3(1-2):171-80
pubmed: 18404431
J Biol Chem. 2010 Mar 5;285(10):7176-86
pubmed: 19858205
Pharmacol Rev. 2010 Dec;62(4):726-59
pubmed: 21079042
J Biol Chem. 1990 Aug 15;265(23):13584-8
pubmed: 2116408
FASEB J. 2012 Jun;26(6):2253-76
pubmed: 22362896
Blood. 2012 May 10;119(19):4430-40
pubmed: 22438251
Clin Dev Immunol. 2012;2012:925135
pubmed: 22474485
Annu Rev Immunol. 2013;31:443-73
pubmed: 23298205
Cytometry A. 2013 May;83(5):439-40
pubmed: 23450796
PLoS One. 2013 Oct 04;8(10):e74946
pubmed: 24124462
Cancer Immunol Immunother. 2014 Jan;63(1):67-72
pubmed: 24213679
World J Biol Chem. 2013 Nov 26;4(4):91-101
pubmed: 24340132
Eur J Immunol. 2014 Jun;44(6):1644-61
pubmed: 24752698
J Immunol. 2014 Jun 1;192(11):5390-7
pubmed: 24771851
PLoS One. 2016 Mar 17;11(3):e0151509
pubmed: 26986619
Annu Rev Immunol. 2016 May 20;34:317-34
pubmed: 27168241
Trends Immunol. 2016 Nov;37(11):803-811
pubmed: 27623114
Immunol Lett. 2016 Nov;179:80-84
pubmed: 27666013
Oncotarget. 2016 Nov 15;7(46):74602-74611
pubmed: 27806341
J Mol Med (Berl). 2017 Sep;95(9):915-925
pubmed: 28547076
J Immunol. 1985 Apr;134(4):2281-6
pubmed: 2982943
Biochemistry. 1985 Apr 9;24(8):2048-58
pubmed: 3893542
J Cell Biol. 1995 Nov;131(3):775-89
pubmed: 7593196
J Clin Immunol. 1993 Mar;13(2):113-8
pubmed: 8100570
J Immunol. 1994 Feb 15;152(4):1509-14
pubmed: 8120365
Biochem J. 1994 Jan 15;297 ( Pt 2):269-75
pubmed: 8297330
Biochem Biophys Res Commun. 1993 Mar 15;191(2):601-9
pubmed: 8461016
EMBO J. 1996 Oct 15;15(20):5481-91
pubmed: 8896442
J Leukoc Biol. 1997 Jan;61(1):73-9
pubmed: 9000539
N Engl J Med. 1998 Feb 12;338(7):436-45
pubmed: 9459648
Leukemia. 1998 Apr;12(4):499-504
pubmed: 9557607