Challenging the prognostic impact of the new WHO and TNM classifications with special emphasis on HPV status in penile carcinoma.


Journal

Virchows Archiv : an international journal of pathology
ISSN: 1432-2307
Titre abrégé: Virchows Arch
Pays: Germany
ID NLM: 9423843

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 18 02 2019
accepted: 25 03 2019
revised: 12 03 2019
pubmed: 12 4 2019
medline: 28 7 2019
entrez: 12 4 2019
Statut: ppublish

Résumé

The evidence concerning prognostic parameters for clinical decision-making in penile cancer is either weak or missing. We therefore analysed the prognostic value of the revised TNM and WHO classification systems on relapse and survival with special emphasis on HPV status. We collected clinical data and tissue samples of 121 patients from centres in Germany and Russia. HPV genotyping and p16

Identifiants

pubmed: 30972551
doi: 10.1007/s00428-019-02566-0
pii: 10.1007/s00428-019-02566-0
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Pagination

211-221

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Auteurs

Sebastian Hölters (S)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
SERVA Electrophoresis GmbH, Heidelberg, Germany.

Oybek Khalmurzaev (O)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Department of Urology, Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" оf the Ministry of Health of the Russian Federation, Moscow, Russian Federation.

Alexey Pryalukhin (A)

Institute of Pathology, Saarland University Medical Centre, Homburg, Germany.
Institute of Pathology, University Medical Centre Bonn, Bonn, Germany.

Philine Loertzer (P)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.

Martin Janssen (M)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.

Julia Heinzelbecker (J)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.

Stefan Ueberdiek (S)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.

Thorsten Pfuhl (T)

Institute of Virology, Saarland University, Homburg, Germany.

Sigrun Smola (S)

Institute of Virology, Saarland University, Homburg, Germany.

Abbas Agaimy (A)

Institute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.

Carol Geppert (C)

Institute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.

Hagen Loertzer (H)

Clinic of Urology and Paediatric Urology, Westpfalz-Klinikum, Kaiserslautern, Germany.

Xaver Krah (X)

Clinic of Urology, Helios Kliniken, Blankenhain, Germany.

Heiko Wunderlich (H)

Clinic of Urology and Paediatric Urology, St. Georg Klinikum, Eisenach, Germany.

Stefan Wagenpfeil (S)

Institute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, Homburg, Germany.

Rainer M Bohle (RM)

Institute of Pathology, Saarland University Medical Centre, Homburg, Germany.

Michael Stöckle (M)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.

Vsevolod Matveev (V)

Department of Urology, Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" оf the Ministry of Health of the Russian Federation, Moscow, Russian Federation.

Arndt Hartmann (A)

Institute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.

Kerstin Junker (K)

Department of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany. kerstin.junker@uks.eu.

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