Adenosine and the Cardiovascular System.
Journal
American journal of cardiovascular drugs : drugs, devices, and other interventions
ISSN: 1179-187X
Titre abrégé: Am J Cardiovasc Drugs
Pays: New Zealand
ID NLM: 100967755
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
pubmed:
12
4
2019
medline:
27
2
2020
entrez:
12
4
2019
Statut:
ppublish
Résumé
Adenosine is an endogenous nucleoside with a short half-life that regulates many physiological functions involving the heart and cardiovascular system. Among the cardioprotective properties of adenosine are its ability to improve cholesterol homeostasis, impact platelet aggregation and inhibit the inflammatory response. Through modulation of forward and reverse cholesterol transport pathways, adenosine can improve cholesterol balance and thereby protect macrophages from lipid overload and foam cell transformation. The function of adenosine is controlled through four G-protein coupled receptors: A
Identifiants
pubmed: 30972618
doi: 10.1007/s40256-019-00345-5
pii: 10.1007/s40256-019-00345-5
pmc: PMC6773474
mid: NIHMS1032832
doi:
Substances chimiques
Cholesterol
97C5T2UQ7J
Adenosine
K72T3FS567
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
449-464Subventions
Organisme : American Heart Association-American Stroke Association
ID : 16GRNT26430041
Pays : United States
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