The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions.

Animals Communicable Diseases / pathology Disease Models, Animal Genetic Predisposition to Disease Genetic Variation Host-Pathogen Interactions Mice Systems Biology / methods
Collaborative Cross genetics reference populations immune genes immunity infection

Journal

Cell host & microbe
ISSN: 1934-6069
Titre abrégé: Cell Host Microbe
Pays: United States
ID NLM: 101302316

Informations de publication

Date de publication:
10 04 2019
Historique:
entrez: 12 4 2019
pubmed: 12 4 2019
medline: 22 11 2019
Statut: ppublish

Résumé

Host genetic variation has a major impact on infectious disease susceptibility. The study of pathogen resistance genes, largely aided by mouse models, has significantly advanced our understanding of infectious disease pathogenesis. The Collaborative Cross (CC), a newly developed multi-parental mouse genetic reference population, serves as a tractable model system to study how pathogens interact with genetically diverse populations. In this review, we summarize progress utilizing the CC as a platform to develop improved models of pathogen-induced disease and to map polymorphic host response loci associated with variation in susceptibility to pathogens.

Identifiants

DOI: 10.1016/j.chom.2019.03.009 PMID: 30974083 PMC: PMC6494101
pubmed: 30974083
pii: S1931-3128(19)30161-1
doi: 10.1016/j.chom.2019.03.009
pmc: PMC6494101
mid: NIHMS1525189
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

484-498

Subventions

Organisme : NIAID NIH HHS
ID : P01 AI132130
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007419
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI100625
Pays : United States

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Références

Mamm Genome. 2018 Feb;29(1-2):80-89
pubmed: 29279960
mBio. 2016 Sep 20;7(5):
pubmed: 27651361
Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1124-34
pubmed: 21427413
Ann Intern Med. 2013 Feb 19;158(4):235-45
pubmed: 23420232
BMC Genet. 2004 Apr 29;5:7
pubmed: 15117419
G3 (Bethesda). 2014 Oct 23;4(12):2353-63
pubmed: 25344410
Immunity. 2015 Jan 20;42(1):18-27
pubmed: 25607456
Proc Biol Sci. 2015 Dec 22;282(1821):20143003
pubmed: 26702034
Cell Host Microbe. 2015 Jan 14;17(1):72-84
pubmed: 25532804
J Infect Dis. 2015 Dec 15;212(12):2011-20
pubmed: 26063222
Genome Med. 2015 Feb 23;7(1):16
pubmed: 25709717
Cell. 2014 Apr 10;157(2):499-513
pubmed: 24725414
Nature. 2016 Jun 15;534(7608):500-5
pubmed: 27309819
G3 (Bethesda). 2014 Sep 18;4(9):1623-33
pubmed: 25237114
Nat Microbiol. 2016 Nov 28;2:16221
pubmed: 27892936
Nature. 2012 Sep 20;489(7416):443-6
pubmed: 22895189
PLoS One. 2013 Dec 06;8(12):e82865
pubmed: 24324838
G3 (Bethesda). 2018 Feb 2;8(2):427-445
pubmed: 29187420
Mamm Genome. 2012 Oct;23(9-10):713-8
pubmed: 22892839
Curr Opin Virol. 2013 Oct;3(5):531-6
pubmed: 23933004
Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9322-7
pubmed: 12080145
Bioinformatics. 2017 Oct 01;33(19):3088-3090
pubmed: 28575171
Brief Funct Genomic Proteomic. 2007 Jun;6(2):91-103
pubmed: 17584761
Nat Genet. 2004 Nov;36(11):1133-7
pubmed: 15514660
Transplantation. 1971 Mar;11(3):325-7
pubmed: 5558564
BMC Genomics. 2018 Apr 27;19(1):303
pubmed: 29703142
J Virol. 2009 Oct;83(20):10417-26
pubmed: 19706712
PLoS Genet. 2015 Oct 09;11(10):e1005504
pubmed: 26452100
Future Microbiol. 2010 Apr;5(4):563-9
pubmed: 20353298
Cell Rep. 2017 Nov 21;21(8):2313-2325
pubmed: 29166619
mBio. 2015 May 26;6(3):e00638-15
pubmed: 26015500
Genome Res. 2011 Aug;21(8):1239-48
pubmed: 21493779
Comp Med. 2017 Jun 1;67(3):253-262
pubmed: 28662754
BMC Genomics. 2016 Feb 27;17:143
pubmed: 26921172
Methods Mol Biol. 2013;1064:315-36
pubmed: 23996268
Science. 2014 Nov 21;346(6212):987-91
pubmed: 25359852
Semin Immunol. 2014 Dec;26(6):454-70
pubmed: 25453225
Genetics. 2005 Oct;171(2):673-81
pubmed: 16085706
Mamm Genome. 2007 Jul;18(6-7):473-81
pubmed: 17674098
G3 (Bethesda). 2017 Jun 7;7(6):1653-1663
pubmed: 28592648
Cell. 1993 May 7;73(3):469-85
pubmed: 8490962
Brief Funct Genomics. 2011 Mar;10(2):98-107
pubmed: 21436306
BMC Genet. 2015 Aug 28;16:106
pubmed: 26310945
Lancet. 1998 Jan 3;351(9095):14-8
pubmed: 9433423
G3 (Bethesda). 2012 Feb;2(2):213-21
pubmed: 22384400
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14658-63
pubmed: 26553974
PLoS Pathog. 2016 Jul 11;12(7):e1005732
pubmed: 27399650
Front Med. 2012 Dec;6(4):444-50
pubmed: 23124883
G3 (Bethesda). 2014 Jun 05;4(8):1429-44
pubmed: 24902603
Shock. 2004 Nov;22(5):460-6
pubmed: 15489639
Nat Commun. 2016 Dec 15;7:13760
pubmed: 27976721
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W452-7
pubmed: 22689647
Mamm Genome. 2002 Apr;13(4):175-8
pubmed: 11956758
BMC Genomics. 2012 Aug 20;13:411
pubmed: 22905720
Infect Immun. 1984 Mar;43(3):981-5
pubmed: 6698615
Infect Immun. 2007 Apr;75(4):1545-55
pubmed: 17283094
Methods Mol Biol. 2009;530:423-33
pubmed: 19266333
Genomics. 1998 Jan 15;47(2):180-6
pubmed: 9479490
Bioinformatics. 2010 Dec 1;26(23):2990-2
pubmed: 20966004
PLoS Pathog. 2013 Feb;9(2):e1003196
pubmed: 23468633
Philos Trans R Soc Lond B Biol Sci. 2012 Mar 19;367(1590):840-9
pubmed: 22312051
Clin Infect Dis. 2014 Feb;58(4):470-80
pubmed: 24336911
BMC Genomics. 2014 Oct 06;15:865
pubmed: 25283706
J Exp Med. 1999 Feb 15;189(4):615-25
pubmed: 9989976
Annu Rev Immunol. 2016 May 20;34:121-49
pubmed: 26735698
Nat Genet. 2000 Jan;24(1):23-5
pubmed: 10615122
J Immunol. 1998 Jul 1;161(1):17-26
pubmed: 9647202
Trends Immunol. 2013 Dec;34(12):602-9
pubmed: 23631936
Genes Brain Behav. 2018 Sep;17(7):e12438
pubmed: 29125223
Appl Environ Microbiol. 2012 Apr;78(7):2075-81
pubmed: 22286994
Genetics. 2009 Aug;182(4):1263-77
pubmed: 19474203
Microbiol Immunol. 2017 Apr;61(3-4):107-113
pubmed: 28370181
Mamm Genome. 2014 Apr;25(3-4):95-108
pubmed: 24487921
Genetics. 2017 Jun;206(2):537-556
pubmed: 28592495
Sci Rep. 2016 May 19;6:26437
pubmed: 27193691
PLoS Pathog. 2016 Nov 2;12(11):e1005996
pubmed: 27806117
J Immunol. 2017 Jul 15;199(2):383-388
pubmed: 28696328
Int J Evol Biol. 2013;2013:204240
pubmed: 23533945
Nat Chem Biol. 2018 May;14(5):516-524
pubmed: 29632412
Dis Model Mech. 2015 Sep;8(9):1141-53
pubmed: 26204894
Genes Immun. 2014 Jan;15(1):38-46
pubmed: 24195963
Genes Immun. 2006 Dec;7(8):655-66
pubmed: 17024130
J Clin Immunol. 2018 Jan;38(1):96-128
pubmed: 29226302
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12
pubmed: 23401516
Nat Rev Genet. 2012 Feb 07;13(3):175-88
pubmed: 22310894
J Virol. 2005 Dec;79(24):15351-5
pubmed: 16306606
Conserv Genet. 2018;19(4):995-1005
pubmed: 30100824
G3 (Bethesda). 2017 Jun 7;7(6):1665-1682
pubmed: 28592649
Dis Model Mech. 2008 Jul-Aug;1(1):43-9
pubmed: 19048052
mBio. 2015 May 05;6(3):e00493-15
pubmed: 25944860
Cell. 2014 Mar 27;157(1):142-50
pubmed: 24679532
Genetics. 2012 Feb;190(2):389-401
pubmed: 22345608
Trends Immunol. 2002 Oct;23(10):469-72
pubmed: 12297411
Toxicol Sci. 2017 Jul 1;158(1):48-62
pubmed: 28369613
Heredity (Edinb). 2011 Oct;107(4):283-304
pubmed: 21427751
Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1167-72
pubmed: 25092317
Mamm Genome. 2018 Aug;29(7-8):446-470
pubmed: 29947965

Auteurs

Kelsey E Noll (KE)

Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Martin T Ferris (MT)

Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: mtferris@email.unc.edu.

Mark T Heise (MT)

Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: mark_heisem@med.unc.edu.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladies transmissibles › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Phénomènes biologiques › Interactions hôte-microbes › Interactions hôte-pathogène › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The Collaborative Cross: A Systems Genetics...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Biologie des systèmes › The Collaborative Cross: A Systems Genetics...