The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain

Animals CD4 Antigens / genetics Chromatin Assembly Factor-1 / metabolism DNA (Cytosine-5-)-Methyltransferase 1 / genetics DNA (Cytosine-5-)-Methyltransferases / genetics DNA Methyltransferase 3A Female Gene Expression Regulation Gene Silencing Histone Chaperones / metabolism Histone Deacetylases / metabolism Histones / metabolism Male Mice Protein Domains Retinoblastoma-Binding Protein 4 / metabolism T-Lymphocytes, Cytotoxic / immunology
CAF-1 CD4 DNA methylation DNMT T-cell development cytotoxic T cell epigenetics gene silencing histone chaperone lineage commitment

Journal

Genes & development
ISSN: 1549-5477
Titre abrégé: Genes Dev
Pays: United States
ID NLM: 8711660

Informations de publication

Date de publication:
01 06 2019
Historique:
received: 25 10 2018
accepted: 22 03 2019
pubmed: 13 4 2019
medline: 4 9 2019
entrez: 13 4 2019
Statut: ppublish

Résumé

The transcriptional repression of alternative lineage genes is critical for cell fate commitment. Mechanisms by which locus-specific gene silencing is initiated and heritably maintained during cell division are not clearly understood. To study the maintenance of silent gene states, we investigated how the

Identifiants

DOI: 10.1101/gad.322024.118 PMID: 30975723 PMC: PMC6546056
pubmed: 30975723
pii: gad.322024.118
doi: 10.1101/gad.322024.118
pmc: PMC6546056
doi:

Substances chimiques

CD4 Antigens 0
Chaf1a protein, mouse 0
Chaf1b protein, mouse 0
Chromatin Assembly Factor-1 0
Dnmt3a protein, mouse 0
Histone Chaperones 0
Histones 0
Rbbp4 protein, mouse 0
Retinoblastoma-Binding Protein 4 0
DNA (Cytosine-5-)-Methyltransferase 1 EC 2.1.1.37
DNA (Cytosine-5-)-Methyltransferases EC 2.1.1.37
DNA Methyltransferase 3A EC 2.1.1.37
Dnmt1 protein, mouse EC 2.1.1.37
Histone Deacetylases EC 3.5.1.98

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

669-683

Subventions

Organisme : NCI NIH HHS
ID : P30 CA016087
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM136573
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007308
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI100853
Pays : United States

Informations de copyright

© 2019 Ng et al.; Published by Cold Spring Harbor Laboratory Press.

Références

Mol Cell Biol. 2003 May;23(9):3226-36
pubmed: 12697822
Biochim Biophys Acta. 2011 Apr-Jun;1809(4-6):255-61
pubmed: 21570500
Gene Ther. 2000 Jun;7(12):1063-6
pubmed: 10871756
Nucleic Acids Res. 2019 Jan 8;47(D1):D442-D450
pubmed: 30395289
Nat Biotechnol. 2011 Jan;29(1):24-6
pubmed: 21221095
Nat Rev Genet. 2009 May;10(5):295-304
pubmed: 19308066
Mol Cell. 2003 Feb;11(2):341-51
pubmed: 12620223
Mol Cell Biol. 2001 Mar;21(6):1953-61
pubmed: 11238931
Mol Cell. 2002 Nov;10(5):1083-96
pubmed: 12453416
Science. 2001 Aug 10;293(5532):1074-80
pubmed: 11498575
Nat Commun. 2018 Sep 5;9(1):3593
pubmed: 30185787
Nat Struct Mol Biol. 2008 Sep;15(9):972-9
pubmed: 19172751
Nucleic Acids Res. 2018 Jul 2;46(W1):W537-W544
pubmed: 29790989
Nat Commun. 2018 Sep 5;9(1):3594
pubmed: 30185805
Genes Dev. 2014 Apr 1;28(7):672-82
pubmed: 24696452
Mol Cell Biol. 2002 Jan;22(2):614-25
pubmed: 11756556
Nat Commun. 2016 Mar 24;7:10924
pubmed: 27010239
Genetics. 2017 Jan;205(1):125-137
pubmed: 27838630
Genes Dev. 1996 Apr 15;10(8):1008-20
pubmed: 8608936
Front Immunol. 2017 Mar 22;8:291
pubmed: 28382035
Genes Dev. 2010 Apr 1;24(7):659-69
pubmed: 20360383
Clin Epigenetics. 2018 Feb 9;10:17
pubmed: 29449903
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3873-8
pubmed: 18322012
Cell Res. 2011 Mar;21(3):381-95
pubmed: 21321607
J Immunol. 2018 Jun 15;200(12):3891-3896
pubmed: 29720423
Cell Rep. 2013 Dec 26;5(6):1704-13
pubmed: 24332856
Nat Commun. 2015 Jan 21;6:6033
pubmed: 25607992
Nature. 2015 Dec 10;528(7581):218-24
pubmed: 26659182
Curr Opin Genet Dev. 2017 Oct;46:83-94
pubmed: 28692904
Immunol Rev. 2016 May;271(1):98-113
pubmed: 27088909
Science. 2016 Nov 18;354(6314):909-912
pubmed: 27856912
Cold Spring Harb Perspect Biol. 2014 May 01;6(5):a019133
pubmed: 24789823
Nat Immunol. 2015 Jul;16(7):746-54
pubmed: 26030024
Genes Cells. 2008 Oct;13(10):1027-43
pubmed: 18761674
Nat Methods. 2013 Dec;10(12):1213-8
pubmed: 24097267
Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6796-9
pubmed: 25368180
Nature. 2018 Feb 15;554(7692):387-391
pubmed: 29414941
Nat Genet. 2001 Nov;29(3):332-6
pubmed: 11687799
PLoS Genet. 2006 Nov 3;2(11):e181
pubmed: 17083276
Cell. 1989 Jul 14;58(1):15-25
pubmed: 2546672
Science. 2018 Sep 28;361(6409):1332-1336
pubmed: 30262494
Cell. 1995 Jun 30;81(7):1105-14
pubmed: 7600578
Mol Cell Biol. 2009 Dec;29(24):6353-65
pubmed: 19822659
Cell. 1994 Jun 17;77(6):917-29
pubmed: 8004678
Nucleic Acids Res. 2016 Jun 20;44(11):5083-94
pubmed: 26908650
J Cell Sci. 2010 Aug 15;123(Pt 16):2853-61
pubmed: 20663913
Nat Struct Mol Biol. 2015 Sep;22(9):662-71
pubmed: 26237512
Elife. 2017 Mar 18;6:
pubmed: 28315525
Science. 2008 Feb 8;319(5864):822-5
pubmed: 18258917
J Biol Chem. 2011 Mar 25;286(12):10876-87
pubmed: 21209461
Nat Rev Genet. 2013 Mar;14(3):204-20
pubmed: 23400093
Mol Cell. 2011 Dec 23;44(6):928-41
pubmed: 22195966
Clin Epigenetics. 2012 Mar 12;4(1):5
pubmed: 22414492
J Immunol. 2014 May 15;192(10):4620-7
pubmed: 24729613
Cell. 2015 Sep 24;163(1):230-45
pubmed: 26365490
Nat Neurosci. 2010 Apr;13(4):423-30
pubmed: 20228804
Immunity. 2001 Nov;15(5):763-74
pubmed: 11728338
Nat Cell Biol. 2004 Dec;6(12):1236-44
pubmed: 15543136
Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W170-5
pubmed: 18487274
Nat Immunol. 2017 Aug;18(8):931-939
pubmed: 28604718
J Biol Chem. 2006 Apr 7;281(14):9560-8
pubmed: 16452472
Mol Cell. 2004 Aug 27;15(4):595-605
pubmed: 15327775
Nature. 2015 Jan 15;517(7534):321-6
pubmed: 25592537
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7101-3
pubmed: 23584020
Nat Struct Mol Biol. 2015 Aug;22(8):618-26
pubmed: 26167883

Auteurs

Charles Ng (C)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Martin Aichinger (M)

Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria.

Tung Nguyen (T)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Christy Au (C)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Tariq Najar (T)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Lin Wu (L)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Kai R Mesa (KR)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Will Liao (W)

New York Genome Center, New York, New York 10013, USA.

Jean-Pierre Quivy (JP)

UMR3664, Centre National de la Recherche Scientifique, Equipe Labellisée Ligue Contre le Cancer, Institut Curie, PSL Research University, F-75005 Paris, France.

Benjamin Hubert (B)

New York Genome Center, New York, New York 10013, USA.

Genevieve Almouzni (G)

UMR3664, Centre National de la Recherche Scientifique, Equipe Labellisée Ligue Contre le Cancer, Institut Curie, PSL Research University, F-75005 Paris, France.

Johannes Zuber (J)

Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria.

Dan R Littman (DR)

The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.
Howard Hughes Medical Institute, New York, New York 10016, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes de différenciation des lymphocytes T › Antigènes CD4 › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Chaperons d'histones › Facteur-1 d'assemblage de la chromatine › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines nucléaires › Protéines liant le poly-adp-ribose › DNA (Cytosine-5-)-methyltransferase 1 › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › One-carbon group transferases › Methyltransferases › DNA modification methylases › DNA-Cytosine Methylases › DNA (cytosine-5-)-methyltransferase › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › One-carbon group transferases › Methyltransferases › DNA modification methylases › DNA-Cytosine Methylases › DNA (cytosine-5-)-methyltransferase › DNA methyltransferase 3A › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Chaperons d'histones › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Amidohydrolases › Histone deacetylases › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Histone › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéines de répression › Protéines du groupe Polycomb › Complexe répresseur Polycomb-2 › Protéine-4 de liaison à la protéine du rétinoblastome › The histone chaperone CAF-1 cooperates with...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T cytotoxiques › The histone chaperone CAF-1 cooperates with...