Variability in total serum IgE over 1 year in severe asthmatics.

Asthma IgE Variability

Journal

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
ISSN: 1710-1484
Titre abrégé: Allergy Asthma Clin Immunol
Pays: England
ID NLM: 101244313

Informations de publication

Date de publication:
2019
Historique:
received: 05 06 2018
accepted: 04 03 2019
entrez: 13 4 2019
pubmed: 13 4 2019
medline: 13 4 2019
Statut: epublish

Résumé

Immunoglobulin E (IgE) is the treatment target of omalizumab, a monoclonal antibody indicated in the treatment of severe allergic asthma. Long-term variability of serum total IgE (sIgE In this prospective study, sIgE The variation in sIgE In severe asthmatics, limited within-patient variability of sIgE

Sections du résumé

BACKGROUND BACKGROUND
Immunoglobulin E (IgE) is the treatment target of omalizumab, a monoclonal antibody indicated in the treatment of severe allergic asthma. Long-term variability of serum total IgE (sIgE
METHODS METHODS
In this prospective study, sIgE
RESULTS RESULTS
The variation in sIgE
CONCLUSION CONCLUSIONS
In severe asthmatics, limited within-patient variability of sIgE

Identifiants

pubmed: 30976287
doi: 10.1186/s13223-019-0331-8
pii: 331
pmc: PMC6441212
doi:

Types de publication

Journal Article

Langues

eng

Pagination

20

Déclaration de conflit d'intérêts

GB, RL, AM, OM and CP are members of an Advisory Board of Novartis Pharma, Belgium. IA and KD work for Matrix45, LLC. By company policy employees are prohibited from owning equity in or perform services independently for sponsor organizations. Matrix45 provides similar services to other biopharmaceutical on a non-exclusivity basis. SG, AP, JVS and SV are employees of Novartis Pharma, Belgium.

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Auteurs

Renaud Louis (R)

1Service de Pneumologie-Allergologie, CHU Sart Tilman B35, 4000 Liege, Belgium.

Charles Pilette (C)

2Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium.

Olivier Michel (O)

3CHU Brugmann, Place A.Van Gehuchten 4, 1020 Brussels, Belgium.

Alain Michils (A)

4CUB Hôpital Erasme, Route de Lennik 808, 1070 Brussels, Belgium.

Guy Brusselle (G)

5UZ Gent, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

Antoine Poskin (A)

6Novartis Pharma, Medialaan 40, 1800 Vilvoorde, Belgium.

Jan Van Schoor (J)

6Novartis Pharma, Medialaan 40, 1800 Vilvoorde, Belgium.

Kris Denhaerynck (K)

Matrix45, LLC, 6159 West Sunset Road, Tucson, AZ 85743 USA.
8University of Basel, Basel, Switzerland.

Stefaan Vancayzeele (S)

6Novartis Pharma, Medialaan 40, 1800 Vilvoorde, Belgium.

Ivo Abraham (I)

Matrix45, LLC, 6159 West Sunset Road, Tucson, AZ 85743 USA.

Sandra Gurdain (S)

6Novartis Pharma, Medialaan 40, 1800 Vilvoorde, Belgium.

Classifications MeSH