Acne and obesity: A nationwide study of 600,404 adolescents.
acne
adolescents
body mass index
obesity
odds
overweight
youths
Journal
Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
17
11
2018
revised:
22
03
2019
accepted:
03
04
2019
pubmed:
13
4
2019
medline:
24
1
2020
entrez:
13
4
2019
Statut:
ppublish
Résumé
The association between body mass index (BMI) and acne is unclear. To determine the association between BMI and acne in youths. A nationwide, population-based, cross-sectional study was conducted in 2002-2015 by using medical data on 600,404 youths during compulsory military service. BMI was measured at age 17 years. Acne was diagnosed by dermatologists. Unadjusted and adjusted odds ratios (aORs) of acne in relation to BMI (stratified into 8 groups) were calculated, with the low-normal group (18.5≤ BMI ≤21.99 kg/m The study included 299,163 males (49.9%) and 301,241 females (50.1%) with a mean age of 18.9 years (standard deviation, 0.6) and 18.7 years (standard deviation, 0.5), respectively, at recruitment. Acne was diagnosed in 55,842 males (18.7%) and 48,969 females (16.3%). The proportion of participants with acne decreased gradually from the underweight to the severely obese group (males, from 19.9% to 13.9%; females, from 16.9% to 11.3%). The findings on multivariable analysis were similar to the unadjusted analysis results, showing the lowest odds of acne in severely obese participants (aOR for males, 0.53; 95% confidence interval, 0.42-0.64; aOR for females, 0.5; 95% confidence interval, 0.37-0.62). The findings persisted in the sensitivity analyses. Information was lacking on potential confounders and acne severity. In youths, overweight and obesity are inversely associated with acne in a dose-dependent manner.
Sections du résumé
BACKGROUND
BACKGROUND
The association between body mass index (BMI) and acne is unclear.
OBJECTIVE
OBJECTIVE
To determine the association between BMI and acne in youths.
METHODS
METHODS
A nationwide, population-based, cross-sectional study was conducted in 2002-2015 by using medical data on 600,404 youths during compulsory military service. BMI was measured at age 17 years. Acne was diagnosed by dermatologists. Unadjusted and adjusted odds ratios (aORs) of acne in relation to BMI (stratified into 8 groups) were calculated, with the low-normal group (18.5≤ BMI ≤21.99 kg/m
RESULTS
RESULTS
The study included 299,163 males (49.9%) and 301,241 females (50.1%) with a mean age of 18.9 years (standard deviation, 0.6) and 18.7 years (standard deviation, 0.5), respectively, at recruitment. Acne was diagnosed in 55,842 males (18.7%) and 48,969 females (16.3%). The proportion of participants with acne decreased gradually from the underweight to the severely obese group (males, from 19.9% to 13.9%; females, from 16.9% to 11.3%). The findings on multivariable analysis were similar to the unadjusted analysis results, showing the lowest odds of acne in severely obese participants (aOR for males, 0.53; 95% confidence interval, 0.42-0.64; aOR for females, 0.5; 95% confidence interval, 0.37-0.62). The findings persisted in the sensitivity analyses.
LIMITATIONS
CONCLUSIONS
Information was lacking on potential confounders and acne severity.
CONCLUSION
CONCLUSIONS
In youths, overweight and obesity are inversely associated with acne in a dose-dependent manner.
Identifiants
pubmed: 30978426
pii: S0190-9622(19)30589-4
doi: 10.1016/j.jaad.2019.04.009
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
723-729Informations de copyright
Copyright © 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.