Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI.
electrochemistry
implantable BCI
micro/nano electrode
modified electrode
Journal
Micromachines
ISSN: 2072-666X
Titre abrégé: Micromachines (Basel)
Pays: Switzerland
ID NLM: 101640903
Informations de publication
Date de publication:
11 Apr 2019
11 Apr 2019
Historique:
received:
13
03
2019
revised:
29
03
2019
accepted:
08
04
2019
entrez:
14
4
2019
pubmed:
14
4
2019
medline:
14
4
2019
Statut:
epublish
Résumé
Signal recording and stimulation with high spatial and temporal resolution are of increasing interest with the development of implantable brain-computer interfaces (BCIs). However, implantable BCI technology still faces challenges in the biocompatibility and long-term stability of devices after implantation. Due to the cone structure, needle electrodes have advantages in the biocompatibility and stability as nerve recording electrodes. This paper develops the fabrication of Ag needle micro/nano electrodes with a laser-assisted pulling method and modifies the electrode surface by electrochemical oxidation. A significant impedance reduction of the modified Ag/AgCl electrodes compared to the Ag electrodes is demonstrated by the electrochemical impedance spectrum (EIS). Furthermore, the stability of modified Ag/AgCl electrodes is confirmed by cyclic voltammogram (CV) scanning. These findings suggest that these micro/nano electrodes have a great application prospect in neural interfaces.
Identifiants
pubmed: 30979081
pii: mi10040242
doi: 10.3390/mi10040242
pmc: PMC6523908
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Biomaterials. 2007 Sep;28(25):3594-607
pubmed: 17517431
Anal Chem. 2007 Jul 1;79(13):4778-87
pubmed: 17550232
Anal Chem. 2009 Jul 1;81(13):5496-502
pubmed: 19514727
J Neurosci Methods. 2010 Jun 15;189(2):216-29
pubmed: 20399227
Anal Chem. 2012 Mar 20;84(6):2949-54
pubmed: 22339586
Neuron. 2012 Jun 21;74(6):970-4
pubmed: 22726828
Biomaterials. 2013 Nov;34(33):8061-74
pubmed: 23891081
Nat Biotechnol. 2015 Mar;33(3):277-84
pubmed: 25599177
Lab Chip. 2015 Mar 21;15(6):1590-7
pubmed: 25651943
Adv Mater. 2015 Dec 9;27(46):7620-37
pubmed: 26414302
Neuron. 2015 Dec 16;88(6):1136-1148
pubmed: 26627311
J Neurophysiol. 2016 May 1;115(5):2255-64
pubmed: 26912601
J Neural Eng. 2016 Dec;13(6):061003
pubmed: 27762237
Sci Adv. 2017 Jun 09;3(6):e1601649
pubmed: 28630894
Neurophotonics. 2017 Oct;4(4):041502
pubmed: 28721358
Biosens Bioelectron. 2018 Jan 15;99:99-107
pubmed: 28743085
Nature. 2017 Nov 8;551(7679):232-236
pubmed: 29120427
Anal Chem. 2018 Aug 21;90(16):9677-9681
pubmed: 30073830
ACS Appl Mater Interfaces. 2018 Nov 7;10(44):38621-38629
pubmed: 30360085
Micromachines (Basel). 2016 Oct 02;7(10):null
pubmed: 30404352