Increased pancreatic-derived factor (PANDER) levels in gestational diabetes mellitus.
FAM3B
Pancreatic-derived factor
gestational diabetes mellitus
Journal
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN: 1473-0766
Titre abrégé: Gynecol Endocrinol
Pays: England
ID NLM: 8807913
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
pubmed:
16
4
2019
medline:
13
8
2020
entrez:
16
4
2019
Statut:
ppublish
Résumé
The aim of the study was to investigate the pancreatic-derived factor (PANDER) levels in healthy pregnant women and in pregnant women with gestational diabetes mellitus (GDM). A total of 50 women consecutively diagnosed with GDM and 30 randomly selected age-matched and gestational-age-matched healthy pregnant women were included in this cross-sectional study. Serum PANDER levels and other variables were analyzed. The age, the gestational age at the time, the blood sample was obtained and the hemoglobin A1c (HbA1c) levels of the GDM and control groups were similar. The body mass index (BMI), fasting blood glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and serum PANDER levels were significantly higher in the GDM group than the control group. The optimal PANDER cutoff value was 227.2 ng/ml, and the ratios above this value were 100 and 86.6% for sensitivity and specificity, respectively (
Identifiants
pubmed: 30982368
doi: 10.1080/09513590.2019.1599856
doi:
Substances chimiques
Blood Glucose
0
Cytokines
0
FAM3B protein, human
0
Glycated Hemoglobin A
0
Insulin
0
Neoplasm Proteins
0
hemoglobin A1c protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM