Novel Contributors and Mechanisms of Cellular Senescence in Hypertension-Associated Premature Vascular Aging.
blood pressure
cellular senescence
hypertension
vascular aging
Journal
American journal of hypertension
ISSN: 1941-7225
Titre abrégé: Am J Hypertens
Pays: United States
ID NLM: 8803676
Informations de publication
Date de publication:
17 07 2019
17 07 2019
Historique:
received:
06
02
2019
revised:
25
03
2019
accepted:
10
04
2019
pubmed:
16
4
2019
medline:
28
7
2020
entrez:
16
4
2019
Statut:
ppublish
Résumé
Hypertension has been described as a condition of premature vascular aging, relative to actual chronological age. In fact, many factors that contribute to the deterioration of vascular function as we age are accelerated in hypertension. Nonetheless, the precise mechanisms that underlie the aged phenotype of arteries from hypertensive patients and animals remain elusive. Cellular senescence is an age-related physiologic process in which cells undergo irreversible growth arrest. Although controlled senescence negatively regulates cell proliferation and promotes tissue regeneration, uncontrolled senescence can contribute to disease pathogenesis by presenting the senescence-associated secretory phenotype, in which molecules such as proinflammatory cytokines, matrix metalloproteases, and reactive oxygen species are released into tissue microenvironments. This review will address and critically evaluate the current literature on the role of cellular senescence in hypertension, with particular emphasis on cells types that mediate and modulate vascular function and structure.
Identifiants
pubmed: 30982879
pii: 5457632
doi: 10.1093/ajh/hpz052
pmc: PMC6636693
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
709-719Subventions
Organisme : NIGMS NIH HHS
ID : K99 GM118885
Pays : United States
Organisme : NHLBI NIH HHS
ID : P01 HL134604
Pays : United States
Organisme : NIGMS NIH HHS
ID : R00 GM118885
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL143082
Pays : United States
Informations de copyright
© American Journal of Hypertension, Ltd 2019. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Références
Trends Cell Biol. 2000 Dec;10(12):524-30
pubmed: 11121744
Mol Cell Biol Res Commun. 2000 Aug;4(2):117-21
pubmed: 11170842
Circ Res. 2001 Oct 26;89(9):793-8
pubmed: 11679409
Circulation. 2002 Apr 2;105(13):1541-4
pubmed: 11927518
J Cardiovasc Pharmacol. 2002 Dec;40(6):930-7
pubmed: 12451327
Arterioscler Thromb Vasc Biol. 2003 Jan 1;23(1):e1-6
pubmed: 12524240
Exp Cell Res. 1961 Dec;25:585-621
pubmed: 13905658
Exp Cell Res. 1965 Mar;37:614-36
pubmed: 14315085
Mech Ageing Dev. 2003 Aug-Sep;124(8-9):911-9
pubmed: 14499496
Circulation. 2003 Nov 4;108(18):2264-9
pubmed: 14557365
Exp Gerontol. 2003 Oct;38(10):1149-60
pubmed: 14580868
Nephrol Dial Transplant. 2003 Dec;18(12):2474-8
pubmed: 14605266
Circ Res. 2004 Apr 2;94(6):768-75
pubmed: 14963003
Cell Struct Funct. 2003 Dec;28(6):495-503
pubmed: 15004419
J Cell Sci. 2004 May 1;117(Pt 11):2417-26
pubmed: 15126641
Mol Cell. 2004 May 21;14(4):501-13
pubmed: 15149599
Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1816-22
pubmed: 15308550
J Hypertens. 2005 Jan;23(1):97-104
pubmed: 15643130
Hypertens Res. 2005 Mar;28(3):263-71
pubmed: 16097371
J Hypertens. 2005 Oct;23(10):1831-7
pubmed: 16148606
Hypertens Res. 2005 Sep;28(9):763-72
pubmed: 16419650
Vasc Med. 2005 Jul;10 Suppl 1:S65-71
pubmed: 16444871
Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1297-302
pubmed: 16601235
Cardiovasc Res. 2006 Jul 15;71(2):363-73
pubmed: 16756966
Circ Res. 2006 Jul 21;99(2):156-64
pubmed: 16794190
Circulation. 2006 Aug 29;114(9):953-60
pubmed: 16908765
Nat Rev Mol Cell Biol. 2007 Sep;8(9):729-40
pubmed: 17667954
Cardiovasc Res. 2007 Dec 1;76(3):506-16
pubmed: 17706954
Biogerontology. 2007 Dec;8(6):663-72
pubmed: 17786580
J Exp Med. 2007 Oct 1;204(10):2449-60
pubmed: 17875676
J Hypertens. 2007 Nov;25(11):2185-92
pubmed: 17921808
Front Biosci. 2008 Jan 01;13:2971-9
pubmed: 17981770
Mech Ageing Dev. 2007 Nov-Dec;128(11-12):662-71
pubmed: 18022214
J Cardiovasc Pharmacol. 2007 Oct;50(4):424-33
pubmed: 18049311
Lancet. 2008 May 3;371(9623):1547-9
pubmed: 18321568
Hypertension. 2008 May;51(5):1339-44
pubmed: 18362223
J Endocrinol. 2008 Apr;197(1):55-64
pubmed: 18372232
Cell Biochem Funct. 2008 Jun;26(4):459-66
pubmed: 18383564
Hypertension. 2008 Jul;52(1):123-9
pubmed: 18504326
Hypertens Res. 2008 Apr;31(4):757-65
pubmed: 18633188
Physiology (Bethesda). 2008 Oct;23:248-62
pubmed: 18927201
PLoS Biol. 2008 Dec 2;6(12):2853-68
pubmed: 19053174
Hypertension. 2009 Feb;53(2):417-22
pubmed: 19075096
Nat Cell Biol. 2009 Aug;11(8):973-9
pubmed: 19597488
Exp Gerontol. 2009 Oct;44(10):659-65
pubmed: 19631729
Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1673-84
pubmed: 19749165
J Physiol Pharmacol. 2009 Sep;60(3):41-7
pubmed: 19826180
Annu Rev Pathol. 2010;5:99-118
pubmed: 20078217
J Hypertens. 2010 May;28(5):931-9
pubmed: 20375903
Trends Mol Med. 2010 May;16(5):238-46
pubmed: 20444648
Exp Cell Res. 1991 Jul;195(1):13-9
pubmed: 2055262
Clin Exp Hypertens A. 1991;13(2):277-96
pubmed: 2065467
Biochem Biophys Res Commun. 2010 Sep 3;399(4):637-41
pubmed: 20691162
Exp Gerontol. 2010 Nov;45(11):868-74
pubmed: 20708673
Atherosclerosis. 2010 Nov;213(1):92-101
pubmed: 20832068
Endocrinology. 2011 Feb;152(2):680-8
pubmed: 21190955
Hypertens Res. 2011 Apr;34(4):479-83
pubmed: 21270817
PLoS One. 2011;6(8):e23652
pubmed: 21858192
Circulation. 2011 Sep 20;124(12):1370-81
pubmed: 21875910
Clin Sci (Lond). 2012 Jan;122(1):1-12
pubmed: 21910690
J Vasc Res. 2012;49(1):13-23
pubmed: 21986469
Science. 1990 Sep 28;249(4976):1570-4
pubmed: 2218499
Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C126-34
pubmed: 22555846
Regul Pept. 2012 Aug 20;177(1-3):35-9
pubmed: 22561451
J Physiol. 2012 Jul 15;590(14):3305-16
pubmed: 22570377
Atherosclerosis. 2012 Jul;223(1):1-68
pubmed: 22698795
Age (Dordr). 2013 Aug;35(4):1219-34
pubmed: 22777652
Vasc Cell. 2012 Aug 28;4(1):12
pubmed: 22929066
Atherosclerosis. 2012 Nov;225(1):76-82
pubmed: 22981429
Mech Ageing Dev. 2012 Nov-Dec;133(11-12):647-54
pubmed: 23000105
Biochem Pharmacol. 2012 Dec 15;84(12):1627-34
pubmed: 23000914
Mol Med Rep. 2013 Feb;7(2):598-602
pubmed: 23151623
New Phytol. 2013 Feb;197(3):696-711
pubmed: 23176101
Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20596-601
pubmed: 23184984
Nat Rev Cardiol. 2013 May;10(5):274-83
pubmed: 23478256
Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1313-9
pubmed: 23520167
Mol Med Rep. 2013 Jun;7(6):1865-70
pubmed: 23588928
Mech Ageing Dev. 2013 Jul-Aug;134(7-8):314-20
pubmed: 23612189
Am J Physiol Heart Circ Physiol. 2013 Aug 1;305(3):H344-53
pubmed: 23709602
Hypertension. 2013 Jul;62(1):126-33
pubmed: 23716586
Nature. 2013 Jul 4;499(7456):97-101
pubmed: 23803760
Biochem Biophys Res Commun. 2013 Sep 13;439(1):142-7
pubmed: 23933320
Nat Commun. 2013;4:2300
pubmed: 23939249
Aging Cell. 2014 Feb;13(1):121-30
pubmed: 23957394
Circulation. 2013 Nov 19;128(21):2318-24
pubmed: 24092817
Redox Biol. 2013 Aug 26;1:411-7
pubmed: 24191234
Cell. 2013 Nov 21;155(5):1119-30
pubmed: 24238961
Cell. 2013 Nov 21;155(5):1104-18
pubmed: 24238962
Biogerontology. 2014 Feb;15(1):47-64
pubmed: 24243065
Hypertension. 2014 Mar;63(3):e40-5
pubmed: 24379182
Genes Dev. 2014 Jan 15;28(2):99-114
pubmed: 24449267
J Hypertens. 2014 Jun;32(6):1293-9
pubmed: 24686009
Sci Transl Med. 2014 Apr 9;6(231):231ra47
pubmed: 24718857
Atherosclerosis. 2014 Sep;236(1):101-7
pubmed: 25016364
EMBO Rep. 2014 Aug;15(8):839-52
pubmed: 25027988
Nagoya J Med Sci. 2014 Feb;76(1-2):35-49
pubmed: 25129990
J Clin Invest. 2014 Oct;124(10):4642-56
pubmed: 25244096
Exp Gerontol. 2015 Aug;68:3-7
pubmed: 25281806
J Am Heart Assoc. 2014 Dec 02;3(6):e001384
pubmed: 25468655
Aging Cell. 2015 Feb;14(1):35-48
pubmed: 25510159
Circ Res. 2015 Jan 30;116(3):480-8
pubmed: 25634971
Pharmacol Biochem Behav. 2015 Jun;133:132-45
pubmed: 25869103
Cardiovasc Res. 2015 Jul 1;107(1):119-30
pubmed: 25910936
Hypertension. 2015 Jul;66(1):175-82
pubmed: 25941345
Curr Hypertens Rev. 2015;11(2):100-9
pubmed: 26022209
Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):1963-74
pubmed: 26139463
Aging (Albany NY). 2015 Oct;7(10):766-75
pubmed: 26539975
Nat Med. 2015 Dec;21(12):1400-5
pubmed: 26646496
Nat Med. 2015 Dec;21(12):1424-35
pubmed: 26646499
Nat Med. 2016 Jan;22(1):78-83
pubmed: 26657143
Circulation. 2016 Jan 26;133(4):e38-360
pubmed: 26673558
Science. 2015 Dec 4;350(6265):1214-5
pubmed: 26785481
Nature. 2016 Feb 11;530(7589):184-9
pubmed: 26840489
Aging Cell. 2016 Oct;15(5):973-7
pubmed: 26864908
Hypertension. 2016 May;67(5):1006-13
pubmed: 26975704
Twin Res Hum Genet. 2016 Oct;19(5):422-9
pubmed: 27515284
J Am Heart Assoc. 2016 Aug 30;5(9):
pubmed: 27577581
Nat Rev Nephrol. 2017 Feb;13(2):77-89
pubmed: 28029153
Nat Commun. 2017 Feb 23;8:14532
pubmed: 28230051
Circulation. 2017 May 30;135(22):2155-2162
pubmed: 28330983
Cell. 2017 Mar 23;169(1):132-147.e16
pubmed: 28340339
Physiology (Bethesda). 2017 May;32(3):224-233
pubmed: 28404738
Hypertension. 2017 Oct;70(4):660-667
pubmed: 28784646
Mol Med Rep. 2017 Nov;16(5):7657-7664
pubmed: 28944849
Int Heart J. 2017 Oct 21;58(5):666-673
pubmed: 28966332
In Vitro Cell Dev Biol. 1989 Feb;25(2):183-92
pubmed: 2921236
Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):709-720
pubmed: 29466710
Am J Physiol Heart Circ Physiol. 2018 Jul 1;315(1):H1-H5
pubmed: 29547021
Hypertension. 2018 May;71(5):877-885
pubmed: 29581213
J Hypertens. 2018 Nov;36(11):2226-2236
pubmed: 30256768
Int J Mol Sci. 2018 Sep 27;19(10):null
pubmed: 30261683
Eur J Pharmacol. 2019 Jan 15;843:96-103
pubmed: 30352200
Circ Res. 2018 Sep 14;123(7):803-824
pubmed: 30355077
J Mol Cell Cardiol. 2019 Feb;127:74-82
pubmed: 30502348
Hypertension. 2019 Feb;73(2):458-468
pubmed: 30624990
Hypertension. 2019 Mar;73(3):514-521
pubmed: 30661480
Biochem Biophys Res Commun. 1993 Sep 15;195(2):1070-6
pubmed: 7690550
Mech Ageing Dev. 1993 Oct 1;71(1-2):73-84
pubmed: 8309284
Exp Cell Res. 1993 Sep;208(1):270-4
pubmed: 8359220
Exp Cell Res. 1993 Apr;205(2):396-402
pubmed: 8482345
Prostaglandins. 1997 Jul;54(1):447-62
pubmed: 9271783
Circ Res. 1998 Apr 6;82(6):704-12
pubmed: 9546379