Bladder Carcinoma Associated with BK Virus in a Renal Allograft Recipient.
BK virus nephropathy
bladder malignancy
polyomavirus
renal allograft recipient
urothelial carcinoma
Journal
Indian journal of nephrology
ISSN: 0971-4065
Titre abrégé: Indian J Nephrol
Pays: India
ID NLM: 8914356
Informations de publication
Date de publication:
Historique:
entrez:
16
4
2019
pubmed:
16
4
2019
medline:
16
4
2019
Statut:
ppublish
Résumé
Bladder carcinoma is a relatively rare carcinoma reported in renal allograft recipients. While many oncogenic viruses have been implicated as causative factors for certain malignancies, questions have been raised about possible role of BK virus in pathogenesis of urothelial cancers. In this report, we have described a patient who developed BK virus nephropathy followed 3 years later by bladder carcinoma. Interestingly, while the tumor tissue demonstrated BK virus, the adjacent normal urothelium was stained negative for BK virus. Considering the viral potential to inhibit tumor suppressors and its differential localization within tumor tissue, it is possible that the virus contributes to tumorigenesis.
Identifiants
pubmed: 30983757
doi: 10.4103/ijn.IJN_434_17
pii: IJN-29-135
pmc: PMC6440321
doi:
Types de publication
Case Reports
Langues
eng
Pagination
135-139Déclaration de conflit d'intérêts
There are no conflicts of interest.
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