Endocrine Disrupting Chemicals: Effects on Endocrine Glands.
adrenal gland
endocrine disruptors
endocrine system
hormones
ovary
pituitary gland
testis
thyroid
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2019
2019
Historique:
received:
28
11
2018
accepted:
01
03
2019
entrez:
16
4
2019
pubmed:
16
4
2019
medline:
16
4
2019
Statut:
epublish
Résumé
In recent years, endocrine disrupting chemicals have gained interest in human physiopathology and more and more studies aimed to explain how these chemicals compounds affect endocrine system. In human populations, the majority of the studies point toward an association between exposure to endocrine disrupting chemicals and the disorders affecting endocrine axis. A great number of endocrine disrupting chemicals seem to be able to interfere with the physiology of hypothalamus-pituitary-gonadal axis; however, every endocrine axis may be a target for each EDCs and their action is not limited to a single axis or organ. Several compounds may also have a negative impact on energy metabolic homeostasis altering adipose tissue and promoting obesity, metabolic syndrome, and diabetes. Different mechanism have been proposed to explain these associations but their complexity together with the degree of occupational or environmental exposure, the low standardization of the studies, and the presence of confounding factors have prevented to establish causal relationship between the endocrine disorders and exposure to specific toxicants so far. This manuscript aims to review the state of art of scientific literature regarding the effects of endocrine-disrupting chemicals (EDCs) on endocrine system.
Identifiants
pubmed: 30984107
doi: 10.3389/fendo.2019.00178
pmc: PMC6448049
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
178Références
Hum Reprod. 2001 May;16(5):972-8
pubmed: 11331648
APMIS. 2003 Jan;111(1):1-9; discussion 9-11
pubmed: 12752226
J Clin Endocrinol Metab. 2005 Feb;90(2):700-6
pubmed: 15572417
Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):501-5
pubmed: 16005920
Environ Health Perspect. 2006 Aug;114(8):1276-82
pubmed: 16882539
J Clin Endocrinol Metab. 2007 May;92(5):1891-6
pubmed: 17244780
Ann Ist Super Sanita. 2008;44(1):57-63
pubmed: 18469377
Eur J Endocrinol. 2008 Dec;159(6):699-703
pubmed: 18787049
J Mol Endocrinol. 2009 Jul;43(1):1-10
pubmed: 19211731
Clin Endocrinol (Oxf). 2009 Oct;71(4):459-65
pubmed: 19222487
Eur J Endocrinol. 2009 Nov;161(5):799-804
pubmed: 19684062
Proc Jpn Acad Ser B Phys Biol Sci. 2010;86(1):40-53
pubmed: 20075607
Hormones (Athens). 2010 Jan-Mar;9(1):16-27
pubmed: 20363718
Front Neuroendocrinol. 2010 Oct;31(4):420-39
pubmed: 20609371
Eur J Endocrinol. 2010 Oct;163(4):509-13
pubmed: 20621957
J Mol Endocrinol. 2011 Feb;46(1):R11-32
pubmed: 21322125
Int J Androl. 2011 Aug;34(4 Pt 2):e68-84; discussion e84-5
pubmed: 21668838
Int J Environ Res Public Health. 2011 Jun;8(6):2265-303
pubmed: 21776230
J Toxicol Environ Health B Crit Rev. 2011;14(5-7):346-69
pubmed: 21790316
J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):204-15
pubmed: 21899826
J Clin Res Pediatr Endocrinol. 2012 Jun;4(2):51-60
pubmed: 22672860
Endocrinology. 2012 Sep;153(9):4097-110
pubmed: 22733974
Exp Suppl. 2012;101:315-60
pubmed: 22945574
J Environ Public Health. 2012;2012:713696
pubmed: 22991565
Asian J Androl. 2013 Mar;15(2):165-8
pubmed: 23334198
Gynecol Endocrinol. 2013 May;29(5):444-7
pubmed: 23347089
Endocr Rev. 2013 Apr;34(2):239-77
pubmed: 23371967
Asian J Androl. 2013 Mar;15(2):159-61
pubmed: 23416895
Oxid Med Cell Longev. 2013;2013:640673
pubmed: 23577225
Endocr Connect. 2013 Sep 17;2(3):R15-29
pubmed: 23985363
Toxicol Lett. 2013 Dec 16;223(3):295-305
pubmed: 24177261
Endocrine. 2014 Aug;46(3):387-96
pubmed: 24366639
Birth Defects Res B Dev Reprod Toxicol. 2014 Feb;101(1):1-2
pubmed: 24510782
Regul Toxicol Pharmacol. 2014 Jun;69(1):22-40
pubmed: 24530840
J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):217-23
pubmed: 24816231
J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):199-206
pubmed: 25460300
Front Endocrinol (Lausanne). 2015 Mar 04;6:29
pubmed: 25788893
Environ Int. 2015 Oct;83:11-40
pubmed: 26073844
Environ Toxicol Pharmacol. 2015 Jul;40(1):241-58
pubmed: 26164742
Nat Rev Endocrinol. 2015 Nov;11(11):653-61
pubmed: 26391979
Endocr Rev. 2015 Dec;36(6):E1-E150
pubmed: 26544531
Am J Obstet Gynecol. 2016 May;214(5):559-65
pubmed: 26829510
Rev Endocr Metab Disord. 2015 Dec;16(4):341-57
pubmed: 26847433
Biochim Biophys Acta. 2016 Sep;1859(9):1130-1140
pubmed: 26877237
J Clin Endocrinol Metab. 2016 Apr;101(4):1872-9
pubmed: 26963951
Andrology. 2016 Jul;4(4):565-72
pubmed: 27003928
Endocr Disruptors (Austin). 2015 Jan 1;3(1):e1080788
pubmed: 27011951
Environ Health Perspect. 2016 Oct;124(10):1497-1503
pubmed: 27108591
BMJ. 2016 Jun 21;353:i3459
pubmed: 27328830
Endocrinology. 2016 Sep;157(9):3366-73
pubmed: 27501186
Mol Cell Endocrinol. 2017 Dec 5;457:81-88
pubmed: 27998805
Occup Environ Med. 2017 Jul;74(7):502-510
pubmed: 28202579
Int J Environ Res Public Health. 2017 Mar 29;14(4):
pubmed: 28353667
Curr Opin Obstet Gynecol. 2017 Aug;29(4):202-211
pubmed: 28557831
C R Biol. 2017 Sep - Oct;340(9-10):446-452
pubmed: 28826789
Environ Health Perspect. 2017 Sep 01;125(9):096001
pubmed: 28934726
C R Biol. 2017 Sep - Oct;340(9-10):403-405
pubmed: 29126512
C R Biol. 2017 Sep - Oct;340(9-10):410-413
pubmed: 29126513
C R Biol. 2017 Sep - Oct;340(9-10):414-420
pubmed: 29126514
Ann Pediatr Endocrinol Metab. 2017 Dec;22(4):219-225
pubmed: 29301181
Int J Mol Sci. 2018 Jun 02;19(6):null
pubmed: 29865233
Best Pract Res Clin Endocrinol Metab. 2019 Jan 22;:null
pubmed: 30733078