Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus.
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
entrez:
16
4
2019
pubmed:
16
4
2019
medline:
23
4
2019
Statut:
ppublish
Résumé
Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its global prevalence. To conduct a systematic review to estimate the global prevalence of hypertension among EPLWH. PubMed/MEDLINE, Embase, the Cochrane Library, and Global Health databases for relevant publications up till May 25, 2018. Observational studies (cohort or cross-sectional studies) that estimated the prevalence of hypertension among EPLWH. Required data were extracted independently by three reviewers and the main outcome was hypertension prevalence among EPLWH. The 24 (n = 29,987) eligible studies included were conducted in North America, Europe, Africa, and Asia. A low level bias threat to the estimated hypertension prevalence rates was observed. The global prevalence of hypertension among EPLWH was estimated at 42.0% (95% CI 29.6%-55.4%), I = 100%. The subgroup analysis showed that North America has the highest prevalence of hypertension 50.2% (95% CI 29.2% -71.2%) followed by Europe 37.8% (95% CI 30.7%-45.7%) sub-Saharan Africa 31.9% (95% CI 18.5% -49.2%) and Asia 31.0% (95% CI 26.1%-36.3%). We found the mean age of the participants explaining a considerable part of variation in hypertension prevalence. This study demonstrated that two out of five EPLWH are hypertensive. North America appears to have the highest prevalence of hypertension followed by Europe, sub-Saharan Africa (SSA) and Asia respectively. Findings from this study can be utilized to integrate hypertension management to HIV management package. (Registration number: CRD42018103069).
Sections du résumé
BACKGROUND
BACKGROUND
Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its global prevalence.
PURPOSE
OBJECTIVE
To conduct a systematic review to estimate the global prevalence of hypertension among EPLWH.
DATA SOURCES
METHODS
PubMed/MEDLINE, Embase, the Cochrane Library, and Global Health databases for relevant publications up till May 25, 2018.
STUDY SELECTION
METHODS
Observational studies (cohort or cross-sectional studies) that estimated the prevalence of hypertension among EPLWH.
DATA EXTRACTION
METHODS
Required data were extracted independently by three reviewers and the main outcome was hypertension prevalence among EPLWH.
DATA SYNTHESIS
RESULTS
The 24 (n = 29,987) eligible studies included were conducted in North America, Europe, Africa, and Asia. A low level bias threat to the estimated hypertension prevalence rates was observed. The global prevalence of hypertension among EPLWH was estimated at 42.0% (95% CI 29.6%-55.4%), I = 100%. The subgroup analysis showed that North America has the highest prevalence of hypertension 50.2% (95% CI 29.2% -71.2%) followed by Europe 37.8% (95% CI 30.7%-45.7%) sub-Saharan Africa 31.9% (95% CI 18.5% -49.2%) and Asia 31.0% (95% CI 26.1%-36.3%). We found the mean age of the participants explaining a considerable part of variation in hypertension prevalence.
CONCLUSION
CONCLUSIONS
This study demonstrated that two out of five EPLWH are hypertensive. North America appears to have the highest prevalence of hypertension followed by Europe, sub-Saharan Africa (SSA) and Asia respectively. Findings from this study can be utilized to integrate hypertension management to HIV management package. (Registration number: CRD42018103069).
Identifiants
pubmed: 30985651
doi: 10.1097/MD.0000000000015024
pii: 00005792-201904120-00012
pmc: PMC6485838
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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