Colonoscopy and colorectal cancer rates among octogenarians and nonagenarians: nationwide study of US veterans.
Aged, 80 and over
Colonoscopy
/ methods
Colorectal Neoplasms
/ diagnosis
Early Detection of Cancer
/ methods
Female
Humans
Incidence
Male
Prevalence
Retrospective Studies
SEER Program
/ statistics & numerical data
United States
United States Department of Veterans Affairs
/ statistics & numerical data
Veterans
colonoscopy
nonagenarians
octogenarians
veterans
Journal
Clinical interventions in aging
ISSN: 1178-1998
Titre abrégé: Clin Interv Aging
Pays: New Zealand
ID NLM: 101273480
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
17
4
2019
pubmed:
17
4
2019
medline:
29
5
2019
Statut:
epublish
Résumé
According to Surveillance, Epidemiology and End Results (SEER) database, colorectal cancer (CRC) is the fourth most common type of cancer and second highest in cancer-related death after lung cancer. The SEER database is geographically limited, currently present in only 10-12 states. Though this gives a good approximation about the overall direction of CRC incidence and prevalence, we need more nationwide data to compare numbers. Furthermore, colonoscopies and CRC rates in the Veterans Affair (VA) geriatric population have not been studied. Our aim was to study the rate of colonoscopies and CRC in octogenarians and nonagenarians and to find the prevalence of CRC in this population. The goal was to obtain data in this subset of patients in order to further expand CRC screening guidelines. A retrospective data analysis was performed consisting of US male veterans who underwent colonoscopy in the VA Health Care System from 2000 to 2015. A total of 458,224 patients aged ≥80 years were identified from the database between years 2000 and 2015. This was divided into three groups of age 80-84 years (89,621 patients), 85-90 years (248,155 patients), and >90 years (120,448 patients). A total of 81,946 patients underwent colonoscopies of which 9,365 were diagnosed with CRC. There was a statistically significant linear increase in rate of colonoscopies with increase in age suggesting that these veterans who end up living to a higher age eventually get a colonoscopy for one reason or the other. The drop in CRC percentage and prevalence observed in age group 85-90 years is statistically different when compared to that in 80-84 years and >90 years groups; however, its clinical significance remains to be elucidated.
Sections du résumé
BACKGROUND
BACKGROUND
According to Surveillance, Epidemiology and End Results (SEER) database, colorectal cancer (CRC) is the fourth most common type of cancer and second highest in cancer-related death after lung cancer. The SEER database is geographically limited, currently present in only 10-12 states. Though this gives a good approximation about the overall direction of CRC incidence and prevalence, we need more nationwide data to compare numbers. Furthermore, colonoscopies and CRC rates in the Veterans Affair (VA) geriatric population have not been studied.
OBJECTIVES AND METHODS
OBJECTIVE
Our aim was to study the rate of colonoscopies and CRC in octogenarians and nonagenarians and to find the prevalence of CRC in this population. The goal was to obtain data in this subset of patients in order to further expand CRC screening guidelines. A retrospective data analysis was performed consisting of US male veterans who underwent colonoscopy in the VA Health Care System from 2000 to 2015.
RESULTS AND CONCLUSION
CONCLUSIONS
A total of 458,224 patients aged ≥80 years were identified from the database between years 2000 and 2015. This was divided into three groups of age 80-84 years (89,621 patients), 85-90 years (248,155 patients), and >90 years (120,448 patients). A total of 81,946 patients underwent colonoscopies of which 9,365 were diagnosed with CRC. There was a statistically significant linear increase in rate of colonoscopies with increase in age suggesting that these veterans who end up living to a higher age eventually get a colonoscopy for one reason or the other. The drop in CRC percentage and prevalence observed in age group 85-90 years is statistically different when compared to that in 80-84 years and >90 years groups; however, its clinical significance remains to be elucidated.
Identifiants
pubmed: 30988602
doi: 10.2147/CIA.S192497
pii: cia-14-609
pmc: PMC6440444
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
609-614Déclaration de conflit d'intérêts
Disclosure The authors report conflicts of interest in this work.
Références
J Clin Oncol. 2009 Jun 10;27(17):2758-65
pubmed: 19403886
Cancer. 2010 Feb 1;116(3):544-73
pubmed: 19998273
Med Care. 2014 Apr;52(4):e21-9
pubmed: 22437619
N Engl J Med. 2014 Apr 3;370(14):1287-97
pubmed: 24645800
Ann Intern Med. 2014 Jun 3;160(11):750-9
pubmed: 24887616
Dig Dis Sci. 2015 Mar;60(3):681-91
pubmed: 25740556
BMJ. 2015 Apr 16;350:h1662
pubmed: 25881903
Ann Intern Med. 2017 Jan 3;166(1):18-26
pubmed: 27669524
CA Cancer J Clin. 2017 May 6;67(3):177-193
pubmed: 28248415
J Natl Cancer Inst. 2017 Sep 1;109(9):
pubmed: 28376154