Growth Kinetics of Kyasanur Forest Disease Virus in Mammalian Cell Lines and Development of Plaque Reduction Neutralization Test.
Animals
Antibodies, Neutralizing
/ blood
Antibodies, Viral
/ blood
Cell Line
Cell Line, Tumor
Chiroptera
Chlorocebus aethiops
Cricetinae
Encephalitis Viruses, Tick-Borne
/ growth & development
Humans
Neutralization Tests
/ methods
Real-Time Polymerase Chain Reaction
Swine
Vero Cells
Viral Plaque Assay
/ methods
BHK-21
Kyasanur forest disease virus
growth kinetics
mammalian cell lines
plaque reduction neutralization test
Journal
Vector borne and zoonotic diseases (Larchmont, N.Y.)
ISSN: 1557-7759
Titre abrégé: Vector Borne Zoonotic Dis
Pays: United States
ID NLM: 100965525
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
pubmed:
18
4
2019
medline:
23
7
2020
entrez:
18
4
2019
Statut:
ppublish
Résumé
Kyasanur forest disease virus (KFDV) is a tick-borne flavivirus identified in 1957 in the Karnataka state of India causing fatalities in monkeys and humans. Even after the introduction of a vaccine in the endemic areas, hundreds of cases are reported every year. Being a high-risk category pathogen, the studies on this virus in India were limited till the past decade. The growth characteristics of this virus in various mammalian cell lines have not yet been studied. In this study, we have demonstrated the growth pattern of virus in BHK-21, Vero E6, Vero CCL81, rhabdomyosarcoma, porcine stable kidney, and
Identifiants
pubmed: 30994413
doi: 10.1089/vbz.2018.2405
doi:
Substances chimiques
Antibodies, Neutralizing
0
Antibodies, Viral
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM