[Detection and Analysis of T Lymphocyte Subsets and B Lymphocytes in Patients with Acute Leukemia].


Journal

Zhongguo shi yan xue ye xue za zhi
ISSN: 1009-2137
Titre abrégé: Zhongguo Shi Yan Xue Ye Xue Za Zhi
Pays: China
ID NLM: 101084424

Informations de publication

Date de publication:
Apr 2019
Historique:
entrez: 19 4 2019
pubmed: 19 4 2019
medline: 1 5 2019
Statut: ppublish

Résumé

To investigate the changes of T lymphocyte subsets, B lymphocyte and NK cells in peripheral blood of patients with acute leukemia at different periods and their significance. The peripheral T lymphocyte subsets and B lymphocyte of 95 patients with acute leukemia [(43 cases of acute lymphoblastic leukemia (ALL), 52 cases of acute myeloid leukemia (AML)] and 50 normal people were detected by flow cytometry respectively. The positive rate of CD3 Changes of T lymphocyte subsets, B lymphocytes and NK cells in the patients with newly diagnosed acute leukemia are significant, thus the detection of T lymphocyte cell subsets, B lymphocytes and NK cells can provide some evidences. for evaluation of the disease severity, curative efficiency and prognosis of patients with acute leukemia. 急性白血病患者T、B淋巴细胞的检测与分析. 探讨不同类型的急性白血病患者外周血T淋巴细胞亚群、B淋巴细胞和NK细胞等在疾病的不同时期的变化及其临床意义。. 采用流式细胞术检测95例初诊白血病患者[急性淋巴细胞白血病(ALL)43例,急性髓系白血病(AML)52例]诱导治疗前后及50例正常对照者外周血T淋巴细胞亚群、B淋巴细胞、NK细胞及Treg细胞百分比。. 初诊白血病各组CD3 初诊白血病各组T淋巴细胞亚群、B淋巴细胞和NK细胞的变化明显,完全缓解组的上述指标基本恢复正常,说明T淋巴细胞亚群、B淋巴细胞、NK细胞水平检测在评价急性白血病严重程度、疗效及判断患者预后有一定的临床价值。.

Autres résumés

Type: Publisher (chi)
急性白血病患者T、B淋巴细胞的检测与分析.

Identifiants

pubmed: 30998133
pii: 1009-2137(2019)02-0327-04
doi: 10.19746/j.cnki.issn.1009-2137.2019.02.003
doi:

Types de publication

Journal Article

Langues

chi

Sous-ensembles de citation

IM

Pagination

327-330

Auteurs

Juan Cheng (J)

Department of Hematology, The First Hospital of Lanzhou University, Laznhou 730000, Gansu Province, China,E-mail: chenggu029@163.com.

Hai-Zhen Ma (HZ)

Department of Hematology, The First Hospital of Lanzhou University, Laznhou 730000, Gansu Province, China.

Hao Zhang (H)

Department of Hematology, The First Hospital of Lanzhou University, Laznhou 730000, Gansu Province, China.

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Classifications MeSH