Racial/ethnic differences in experimental pain sensitivity and associated factors - Cardiovascular responsiveness and psychological status.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2019
2019
Historique:
received:
19
10
2018
accepted:
03
04
2019
entrez:
19
4
2019
pubmed:
19
4
2019
medline:
8
1
2020
Statut:
epublish
Résumé
This study evaluated the contributions of psychological status and cardiovascular responsiveness to racial/ethnic differences in experimental pain sensitivity. The baseline measures of 3,159 healthy individuals-non-Hispanic white (NHW): 1,637, African-American (AA): 1,012, Asian: 299, and Hispanic: 211-from the OPPERA prospective cohort study were used. Cardiovascular responsiveness measures and psychological status were included in structural equation modeling based mediation analyses. Pain catastrophizing was a significant mediator for the associations between race/ethnicity and heat pain tolerance, heat pain ratings, heat pain aftersensations, mechanical cutaneous pain ratings and aftersensations, and mechanical cutaneous pain temporal summation for both Asians and AAs compared to NHWs. HR/MAP index showed a significant inconsistent (mitigating) mediating effect on the association between race/ethnicity (AAs vs. NHWs) and heat pain tolerance. Similarly, coping inconsistently mediated the association between race/ethnicity and mechanical cutaneous pain temporal summation in both AAs and Asians, compared to NHWs. The factor encompassing depression, anxiety, and stress was a significant mediator for the associations between race/ethnicity (Asians vs. NHWs) and heat pain aftersensations. Thus, while pain catastrophizing mediated racial/ethnic differences in many of the QST measures, the psychological and cardiovascular mediators were distinctly restrictive, signifying multiple independent mechanisms in racial/ethnic differences in pain.
Identifiants
pubmed: 30998733
doi: 10.1371/journal.pone.0215534
pii: PONE-D-18-30351
pmc: PMC6472780
doi:
Types de publication
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0215534Subventions
Organisme : NIDCR NIH HHS
ID : U01 DE017018
Pays : United States
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Clin J Pain. 2005 Mar-Apr;21(2):147-53
pubmed: 15722808
Auton Neurosci. 2002 Aug 30;99(2):127-33
pubmed: 12241087
Clin J Pain. 2001 Mar;17(1):52-64
pubmed: 11289089
J Pain. 2011 Nov;12(11 Suppl):T12-26
pubmed: 22074749
Pain. 2002 Dec;100(3):291-8
pubmed: 12468000
PLoS One. 2015 Jun 01;10(6):e0127760
pubmed: 26029911
Asian J Psychiatr. 2015 Apr;14:28-30
pubmed: 25701068
Pain. 2013 Jan;154(1):119-23
pubmed: 23149393
Pain Med. 2013 Nov;14(11):1708-18
pubmed: 23889771
Pain Med. 2012 Nov;13(11):1499-508
pubmed: 22994358
Int J Psychophysiol. 2007 Sep;65(3):193-200
pubmed: 17553582
Pain. 2000 Oct;88(1):61-8
pubmed: 11098100
J Behav Med. 2000 Aug;23(4):351-65
pubmed: 10984864
Brain. 2004 Apr;127(Pt 4):835-43
pubmed: 14960499
Neurosci Biobehav Rev. 1984 Fall;8(3):343-67
pubmed: 6095151
Psychosom Med. 2001 Mar-Apr;63(2):316-23
pubmed: 11292281
J Pain. 2017 Oct;18(10):1229-1236
pubmed: 28619697
Prev Chronic Dis. 2010 May;7(3):A64
pubmed: 20394703
Arthritis Rheum. 2012 Dec;64(12):3926-35
pubmed: 23135697
Curr Diab Rep. 2012 Aug;12(4):393-402
pubmed: 22623149
Am Psychol. 2010 May-Jun;65(4):237-51
pubmed: 20455618
Psychophysiology. 2011 Jun;48(6):762-73
pubmed: 21039586
Psychol Bull. 2007 Jul;133(4):581-624
pubmed: 17592957
Pain Med. 2011 Apr;12(4):634-44
pubmed: 21392249
Shanghai Arch Psychiatry. 2013 Dec;25(6):390-4
pubmed: 24991183
J Pain. 2011 Nov;12(11 Suppl):T75-91
pubmed: 22074754
J Aging Health. 2012 Feb;24(1):168-87
pubmed: 21693669
J Pain. 2011 Nov;12(11 Suppl):T61-74
pubmed: 22074753
J Pain. 2004 Aug;5(6):304-16
pubmed: 15336635
BMC Musculoskelet Disord. 2011 Oct 12;12:230
pubmed: 21992460
Pain. 2011 Sep;152(9):2157-64
pubmed: 21696888
Clin J Pain. 1997 Jun;13(2):156-62
pubmed: 9186023
J Health Soc Behav. 1983 Dec;24(4):385-96
pubmed: 6668417
J Pain. 2015 May;16(5):491-7
pubmed: 25725173
Neurosci Biobehav Rev. 2004 Jul;28(4):395-414
pubmed: 15341037
Ann N Y Acad Sci. 2001 Jun;940:324-37
pubmed: 11458690
Pain Med. 2012 Apr;13(4):522-40
pubmed: 22390201
Proc Finn Dent Soc. 1989;85(4-5):395-407
pubmed: 2699765
Pain Med. 2005 Jan-Feb;6(1):18-28
pubmed: 15669947
J Pain. 2011 May;12(5):563-72
pubmed: 21277836
Pain. 2006 Aug;123(3):231-43
pubmed: 16697110
Psychosom Med. 1997 Sep-Oct;59(5):503-11
pubmed: 9316183
Behav Res Methods Instrum Comput. 2004 Nov;36(4):717-31
pubmed: 15641418
Pain. 2006 Feb;120(3):297-306
pubmed: 16427738
Annu Rev Psychol. 2007;58:593-614
pubmed: 16968208
Eur J Pain. 2013 Jul;17(6):903-15
pubmed: 23165778
J Pain. 2011 Nov;12(11 Suppl):T46-60
pubmed: 22074752
Pain Med. 2003 Sep;4(3):277-94
pubmed: 12974827
Pain Pract. 2014 Jul;14(6):532-40
pubmed: 23889982
Biol Psychol. 2008 Feb;77(2):174-82
pubmed: 18023960
J Clin Nurs. 2008 Jun;17(11):1471-80
pubmed: 18298508
Pain. 2017 Feb;158(2):194-211
pubmed: 27682208
Pain Med. 2011 Feb;12(2):314-21
pubmed: 21143756
J Pain. 2004 Apr;5(3):183-91
pubmed: 15106131
Lancet. 1998 Feb 14;351(9101):478-84
pubmed: 9482439
J Pain. 2009 Dec;10(12):1187-204
pubmed: 19944378
J Pain. 2010 Nov;11(11):1187-94
pubmed: 20452836
Compr Psychiatry. 2014 Nov;55(8):1950-9
pubmed: 25217309
J Pain. 2017 Mar;18(3):332-339
pubmed: 27908838
Psychosom Med. 2014 May;76(4):302-10
pubmed: 24804882
J Pain. 2015 Aug;16(8):769-80
pubmed: 26028573
J Womens Health (Larchmt). 2008 Jun;17(5):869-78
pubmed: 18537488