Dwell time verification in brachytherapy based on time resolved in vivo dosimetry.

Dwell times HDR brachytherapy In vivo dosimetry Prostate cancer Treatment verification

Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 06 12 2018
revised: 22 02 2019
accepted: 29 03 2019
entrez: 20 4 2019
pubmed: 20 4 2019
medline: 21 6 2019
Statut: ppublish

Résumé

This paper presents a method to verify dwell times during High Dose Rate (HDR) Brachytherapy (BT) by means of in vivo dosimetry (IVD), and reports on an afterloader's stability in dwell time control. In vivo dosimetry was performed during 20 HDR prostate cancer treatments using a point detector based on a radio-luminescence crystal (Al A total of 3518 dwell positions were analysed. The amount of identified dwell positions were 82%, which increased to 89% if the short dwell times (<1 s) were omitted in the analysis. The largest deviation was -0.4 s seen for a single dwell position, and in 97.1% of the cases, the deviations were <0.15 s. The dwell times in BT are well controlled by the afterloader. It is shown that IVD facilitates the detection of dwell time offsets that could have a clinical impact.

Identifiants

pubmed: 31000077
pii: S1120-1797(19)30075-4
doi: 10.1016/j.ejmp.2019.03.031
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

156-161

Informations de copyright

Copyright © 2019 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Auteurs

J G Johansen (JG)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark. Electronic address: jacjoa@rm.dk.

G Kertzscher (G)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

E B Jørgensen (EB)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

S Rylander (S)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

L Bentzen (L)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

S B Hokland (SB)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

C S Søndergaard (CS)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

A K M With (AKM)

Örebro University Hospital, Örebro, Sweden.

S Buus (S)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

K Tanderup (K)

Department of Oncology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

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Classifications MeSH