Flexicaulin A, An
Animals
Apoptosis
/ drug effects
Cell Line, Tumor
Cell Proliferation
/ drug effects
Cell Survival
/ drug effects
Colorectal Neoplasms
/ drug therapy
Diterpenes, Kaurane
/ chemistry
Flow Cytometry
Gene Expression Regulation, Neoplastic
/ drug effects
HCT116 Cells
Humans
Isodon
/ chemistry
Mice
Plants, Medicinal
/ chemistry
Xenograft Model Antitumor Assays
p21-Activated Kinases
/ genetics
cell cycle arrest
colorectal carcinoma
diterpenoid
ent-kaurane
p21
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 Apr 2019
18 Apr 2019
Historique:
received:
28
03
2019
revised:
15
04
2019
accepted:
15
04
2019
entrez:
21
4
2019
pubmed:
21
4
2019
medline:
14
8
2019
Statut:
epublish
Résumé
Natural products, explicitly medicinal plants, are an important source of inspiration of antitumor drugs, because they contain astounding amounts of small molecules that possess diversifying chemical entities. For instance,
Identifiants
pubmed: 31003485
pii: ijms20081917
doi: 10.3390/ijms20081917
pmc: PMC6514797
pii:
doi:
Substances chimiques
Diterpenes, Kaurane
0
p21-Activated Kinases
EC 2.7.11.1
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Innovation and Technology Commission, Hong Kong Special Administrative Region, China
ID : ITS/254/16
Organisme : Interdisciplinary Research Matching Scheme, Hong Kong Baptist University
ID : RC-IRMS/16-17/02
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