Head and neck carcinoma of unknown primary.

Adenocarcinoma / pathology Adult Carcinoma, Neuroendocrine / pathology Carcinoma, Squamous Cell / pathology Head and Neck Neoplasms / pathology Herpesvirus 4, Human Humans Lymphatic Metastasis Nasopharyngeal Neoplasms / pathology Neck Neoplasms, Unknown Primary / pathology Oropharyngeal Neoplasms / pathology Papillomaviridae Thyroid Neoplasms / pathology
Head and neck tumor Lymph-node metastasis Metastasis of unknown primary

Journal

European annals of otorhinolaryngology, head and neck diseases
ISSN: 1879-730X
Titre abrégé: Eur Ann Otorhinolaryngol Head Neck Dis
Pays: France
ID NLM: 101531465

Informations de publication

Date de publication:
Jun 2019
Historique:
pubmed: 22 4 2019
medline: 27 12 2019
entrez: 22 4 2019
Statut: ppublish

Résumé

In adult cervicofacial pathology, carcinoma of unknown primary is defined as lymph-node metastasis the anatomic origin of which is not known at the time of initial management. It constitutes up to 5% of head and neck cancers. Presentation may suggest benign pathology, delaying and confusing oncologic treatment. Diagnostic strategy in cervical lymph node with suspicion of neoplasia requires exhaustive work-up to diagnose malignancy and, in 45% to 80% of cases, depending on the series, to identify the primary site. Histologic types comprise squamous cell carcinoma, thyroid carcinoma, adenocarcinoma, neuroendocrine carcinoma and undifferentiated carcinoma. Association is sometimes found with human papilloma virus or Epstein Barr virus, guiding treatment. The objective of the present study was to provide clinicians with the necessary diagnostic tools, based on the current state of clinical, imaging and pathologic knowledge, and to detail treatment options.

Identifiants

DOI: 10.1016/j.anorl.2019.04.002 PMID: 31005456
pubmed: 31005456
pii: S1879-7296(19)30062-6
doi: 10.1016/j.anorl.2019.04.002
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

185-192

Informations de copyright

Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Auteurs

T Kennel (T)

Département d'orl et chirurgie cervico faciale, hôpital universitaire Gui de Chauliac, université de Montpellier, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

R Garrel (R)

Département d'orl et chirurgie cervico faciale, hôpital universitaire Gui de Chauliac, université de Montpellier, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France. Electronic address: r-garrel@chu-montpellier.fr.

V Costes (V)

Département de biopathologie cellulaire et tissulaire des tumeurs, équipe médicale anatomie et cytologie pathologiques, hôpital universitaire Gui-de-Chauliac, université de Montpellier, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

P Boisselier (P)

Département de radiothérapie, institut du cancer de Montpellier, 208, avenue des Apothicaires, 34298 Montpellier, France.

L Crampette (L)

Département d'orl et chirurgie cervico faciale, hôpital universitaire Gui de Chauliac, université de Montpellier, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

V Favier (V)

Département d'orl et chirurgie cervico faciale, hôpital universitaire Gui de Chauliac, université de Montpellier, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

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Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroendocrines › Carcinome neuroendocrine › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Tumeurs épidermoïdes › Carcinome épidermoïde › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs de la tête et du cou › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Virus › Virus oncogènes › Virus tumoraux à ADN › Gammaherpesvirinae › Lymphocryptovirus › Herpèsvirus humain de type 4 › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Métastase tumorale › Métastase lymphatique › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies du pharynx › Tumeurs du pharynx › Tumeurs du rhinopharynx › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Régions du corps › Cou › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Métastase tumorale › Métastases d'origine inconnue › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies du pharynx › Tumeurs du pharynx › Tumeurs de l'oropharynx › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Virus › Virus oncogènes › Virus tumoraux à ADN › Papillomaviridae › Head and neck carcinoma of unknown primary.
questionsmedicales.fr › Maladies endocriniennes › Maladies de la thyroïde › Tumeurs de la thyroïde › Head and neck carcinoma of unknown primary.