A pilot study on the efficacy of transcranial direct current stimulation applied to the pharyngeal motor cortex for dysphagia associated with brainstem involvement in multiple sclerosis.

Adult Brain Stem / diagnostic imaging Deglutition Disorders / diagnostic imaging Electromyography / methods Female Humans Male Motor Cortex / diagnostic imaging Multiple Sclerosis / diagnostic imaging Pharynx / diagnostic imaging Pilot Projects Transcranial Direct Current Stimulation / methods Treatment Outcome
Cortico-pharyngeal excitability Cricopharyngeal muscle Multiple sclerosis-associated dysphagia Pharyngeal MEPs Swallowing motor cortex Transcranial direct current stimulation (tDCS)

Journal

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
ISSN: 1872-8952
Titre abrégé: Clin Neurophysiol
Pays: Netherlands
ID NLM: 100883319

Informations de publication

Date de publication:
06 2019
Historique:
received: 14 07 2016
revised: 14 03 2019
accepted: 02 04 2019
pubmed: 23 4 2019
medline: 4 3 2020
entrez: 23 4 2019
Statut: ppublish

Résumé

we investigated the effect of anodal transcranial direct current stimulation (tDCS) applied over the pharyngeal motor area in dysphagia associated with multiple sclerosis (MS). Eighteen MS patients with dysphagia associated with brainstem involvement were randomized to receive either "real" or "sham" tDCS. The Penetration/Aspiration Scale (PAS). changes in electromyographic (EMG) parameters and pharyngeal cortical motor evoked potentials (MEPs). Patients were evaluated at baseline (T the PAS values were significantly lower in the active group than in "sham" group at T Our findings support a beneficial effect of anodal tDCS applied to the pharyngeal motor cortex in MS-associated dysphagia. Considering its safety and efficacy, tDCS may represent an important resource in MS-associated dysphagia.

Identifiants

DOI: 10.1016/j.clinph.2019.04.003 PMID: 31009904
pubmed: 31009904
pii: S1388-2457(19)30124-5
doi: 10.1016/j.clinph.2019.04.003
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1017-1024

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Domenico A Restivo (DA)

Neurological Unit, "Garibaldi" Hospital, Catania, Italy. Electronic address: darestivo@libero.it.

Enrico Alfonsi (E)

Neurophysiological Unit, IRCCS "Fondazione Casimiro Mondino", Pavia, Italy.

Antonino Casabona (A)

Department of Biomedical and Biotechnological Sciences, Section of Physiology, University of Catania, Catania, Italy.

Shaheen Hamdy (S)

School of Translational Medicine-Inflammation Sciences, Faculty of Medical and Human Sciences, University of Manchester (part of the Manchester Academic Health Sciences Centre MAHSC), Salford Royal Hospital, Eccles Old Road, Salford M6 8HD, UK.

Cristina Tassorelli (C)

Neurophysiological Unit, IRCCS "Fondazione Casimiro Mondino", Pavia, Italy.

Mariangela Panebianco (M)

Neurological Unit, "Garibaldi" Hospital, Catania, Italy; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Clinical Sciences Centre for Research and Education, Lower Lane, L9 7LJ Liverpool, UK.

Rosario Marchese-Ragona (R)

ENT Department, University of Padua, Padua, Italy.

Angelo Quartarone (A)

IRCCS Centro Neurolesi "Bonibo-Pulejo", via Provinciale Palermo, Contrada Casazza 95124, Messina, Italy.

Diego Centonze (D)

Laboratory of Synaptic Immunopathology, Department of Systems Medicine, Tor Vergata University, Via Montpellier 1, 00133 Rome, Italy; Unit of Neurology and Neurorehabilitation, IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli, IS, Italy.

Antonino Pavone (A)

Neurological Unit, "Garibaldi" Hospital, Catania, Italy.

Mario Stampanoni Bassi (M)

Unit of Neurology and Neurorehabilitation, IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli, IS, Italy.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Tronc cérébral › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies du pharynx › Troubles de la déglutition › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Myographie › Électromyographie › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Cortex sensorimoteur › Cortex moteur › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Maladies démyélinisantes auto-immunes du SNC › Sclérose en plaques › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Système stomatognathique › Pharynx › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Projets pilotes › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Disciplines et activités comportementales › Techniques psychologiques › Électrochoc › Stimulation transcrânienne par courant continu › A pilot study on the efficacy of transcranial...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › A pilot study on the efficacy of transcranial...