High Prevalence of Diabetes in Patients With Primary Aldosteronism (PA) Associated With Subclinical Hypercortisolism and Prediabetes More Prevalent in Bilateral Than Unilateral PA: A Large, Multicenter Cohort Study in Japan.
Adult
Aged
Aged, 80 and over
Aldosterone
/ blood
Cohort Studies
Cushing Syndrome
/ blood
Diabetes Complications
/ blood
Diabetes Mellitus
/ blood
Female
Glycated Hemoglobin
/ analysis
Humans
Hyperaldosteronism
/ blood
Japan
/ epidemiology
Male
Middle Aged
Prediabetic State
/ blood
Prevalence
Retrospective Studies
Young Adult
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
15
06
2018
accepted:
20
11
2018
entrez:
24
4
2019
pubmed:
24
4
2019
medline:
23
1
2020
Statut:
ppublish
Résumé
To investigate the prevalence and causes of diabetes in patients with primary aldosteronism (PA) in a multi-institutional cohort study in Japan. The prevalence of diabetes was determined in 2,210 patients with PA (diagnosed or glycated hemoglobin [HbA Of the 2,210 patients with PA, 477 (21.6%) had diabetes. This prevalence is higher than that in the general population (12.1%) or in 10-year cohorts aged 30-69 years. Logistic regression or χ Individuals with PA have a high prevalence of diabetes, which is associated mainly with SH. The prevalence of prediabetes is greater for bilateral than unilateral PA, suggesting a unique metabolic cause of bilateral PA.
Identifiants
pubmed: 31010944
pii: dc18-1293
doi: 10.2337/dc18-1293
doi:
Substances chimiques
Glycated Hemoglobin A
0
Aldosterone
4964P6T9RB
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
938-945Informations de copyright
© 2019 by the American Diabetes Association.