Disagreement in cardiac output measurements between fourth-generation FloTrac and critical care ultrasonography in patients with circulatory shock: a prospective observational study.

Cardiac output Critical care ultrasonography Critically ill Intensive care Monitoring Pulse contour analysis Shock

Journal

Journal of intensive care
ISSN: 2052-0492
Titre abrégé: J Intensive Care
Pays: England
ID NLM: 101627304

Informations de publication

Date de publication:
2019
Historique:
received: 17 01 2019
accepted: 14 03 2019
entrez: 24 4 2019
pubmed: 24 4 2019
medline: 24 4 2019
Statut: epublish

Résumé

Cardiac output measurements may inform diagnosis and provide guidance of therapeutic interventions in patients with hemodynamic instability. The FloTrac™ algorithm uses uncalibrated arterial pressure waveform analysis to estimate cardiac output. Recently, a new version of the algorithm has been developed. The aim was to assess the agreement between FloTrac™ and routinely performed cardiac output measurements obtained by critical care ultrasonography in patients with circulatory shock. A prospective observational study was performed in a tertiary hospital from June 2016 to January 2017. Adult critically ill patients with circulatory shock were eligible for inclusion. Cardiac output was measured simultaneously using FloTrac™ with a fourth-generation algorithm (CO Eighty-nine paired cardiac output measurements were performed in 17 patients during their first 24 h of admittance. CO In critically ill patients with circulatory shock, there was disagreement and clinically unacceptable trending ability between values of cardiac output obtained by uncalibrated arterial pressure waveform analysis and critical care ultrasonography. Clinicaltrials.gov, NCT02912624, registered on September 23, 2016.

Sections du résumé

BACKGROUND BACKGROUND
Cardiac output measurements may inform diagnosis and provide guidance of therapeutic interventions in patients with hemodynamic instability. The FloTrac™ algorithm uses uncalibrated arterial pressure waveform analysis to estimate cardiac output. Recently, a new version of the algorithm has been developed. The aim was to assess the agreement between FloTrac™ and routinely performed cardiac output measurements obtained by critical care ultrasonography in patients with circulatory shock.
METHODS METHODS
A prospective observational study was performed in a tertiary hospital from June 2016 to January 2017. Adult critically ill patients with circulatory shock were eligible for inclusion. Cardiac output was measured simultaneously using FloTrac™ with a fourth-generation algorithm (CO
RESULT RESULTS
Eighty-nine paired cardiac output measurements were performed in 17 patients during their first 24 h of admittance. CO
CONCLUSIONS CONCLUSIONS
In critically ill patients with circulatory shock, there was disagreement and clinically unacceptable trending ability between values of cardiac output obtained by uncalibrated arterial pressure waveform analysis and critical care ultrasonography.
TRIAL REGISTRATION BACKGROUND
Clinicaltrials.gov, NCT02912624, registered on September 23, 2016.

Identifiants

pubmed: 31011425
doi: 10.1186/s40560-019-0373-5
pii: 373
pmc: PMC6460822
doi:

Banques de données

ClinicalTrials.gov
['NCT02912624']

Types de publication

Journal Article

Langues

eng

Pagination

21

Investigateurs

Geert Koster (G)
Frederik Keus (F)
Iwan C C van der Horst (ICC)
Willem Dieperink (W)
Roos Bleijendaal (R)
Yasmin F Cawale (YF)
Ramon P Clement (RP)
Devon Dijkhuizen (D)
Ruben J Eck (RJ)
Bart Hiemstra (B)
Anja Haker (A)
Casper D H Hilbink (CDH)
Thomas Kaufmann (T)
Martiene Klasen (M)
Manon Klaver (M)
Laura J Schokking (LJ)
Victor W Sikkens (VW)
Madelon Vos (M)
Justin Woerlee (J)
Renske Wiersema (R)

Déclaration de conflit d'intérêts

The local institutional review board (Medisch Ethische Toetsingscommissie, University Medical Center Groningen) approved the study (M15.168207 and M16.193856). Written informed consent was obtained from all patients.Not applicable.TWLS received honoraria from Edwards Lifesciences (Irvine, California, USA) for consulting and for giving lectures. The other authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Auteurs

Thomas Kaufmann (T)

1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

Ramon P Clement (RP)

1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

Bart Hiemstra (B)

1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
2Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Jaap Jan Vos (JJ)

1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

Thomas W L Scheeren (TWL)

1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

Frederik Keus (F)

2Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Iwan C C van der Horst (ICC)

2Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Classifications MeSH